Pharmacologie
Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antivirals
Auteurs et autrices
Jimena Pérez-Vargas, Gabriel Lemieux, Connor A.H. Thompson, Antoine Désilets, Siobhan Ennis, Guang Gao, Danielle G. Gordon, Annika Lea Schulz, Masahiro Niikura, Ivan Robert Nabi, Mel Krajden, Pierre-Luc Boudreault, Richard Leduc, François Jean
Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice
Auteurs et autrices
Emmeran Le Moal †, Yuguo Liu ‡, Jasmin Collerette-Tremblay ‡, Simon Dumontier, Paul Fabre, Thomas Molina, Junio Dort §, Zakaria Orfi, Nicolas Denault, Joël Boutin, Joris Michaud, Hugo Giguère, Alexandre Desroches, Kien Trân, Benjamin Ellezam, François Vézina, Sonia Bedard, Catherine Raynaud, Frederic Balg, Philippe Sarret, Pierre- Luc Boudreault, Michelle S. Scott, Jean- Bernard Denault, Eric Marsault †, Jerome N. Feige, Mannix Auger- Messier, Nicolas A. Dumont, C. Florian Bentzinger
Motivation to participate and attrition factors in a COVID-19 biobank: A qualitative study
Auteurs et autrices
Laura Jalbert, Anne-Sophie Hautin, Marie Baron, Ève Dubé, Myriam Gagné, Catherine Girard, Catherine Larochelle, Annie LeBlanc, Maxime Sasseville, Simon Décary, Karine Tremblay
Galectin-8 modulates human osteoclast activity partly through isoform-specific interactions
Auteurs et autrices
Michèle Roy, Léopold Mbous Nguimbus, Papa Yaya Badiane, Victor Goguen-Couture, Jade Degrandmaison, Jean-Luc Parent, Marie A Brunet, Sophie Roux
A recurrent de novo MAX p.Arg60Gln variant causes a syndromic overgrowth disorder through differential expression of c-Myc target genes
Auteurs et autrices
Erica L. Harris, Vincent Roy, Martin Montagne, Ailsa M.S. Rose, Helen Livesey, Margot R.F. Reijnders, Emma Hobson, Francis H. Sansbury, Marjolein H. Willemsen, Rolph Pfundt, Daniel Warren, Vernon Long, Ian M. Carr, Han G. Brunner, Eamonn G. Sheridan, Helen V. Firth, Pierre Lavigne, James A. Poulter
Moving towards the implementation of pharmacogenetic testing in Quebec
Auteurs et autrices
Ling Jing Li, Samuel Legeay, Ann-Lorie Gagnon, Marie-Pier Frigon, Laurence Tessier, Karine Tremblay