Pharmacologie
A high-precision view of intercompartmental drug transport via simultaneous, seconds-resolved, in situ measurements in the vein and brain
Auteurs et autrices
Julian Gerson, Murat Kaan Erdal, Philippe Dauphin-Ducharme, Andrea Idili, Joao P. Hespanha, Kevin W. Plaxco, Tod E. Kippin
A dual-color PAX7 and MYF5 in vivo reporter to investigate muscle stem cell heterogeneity in regeneration and aging
Auteurs et autrices
Sara Ancel, Joris Michaud, Federico Sizzano, Loic Tauzin, Manuel Oliveira, Eugenia Migliavacca, Svenja C. Schüler, Sruthi Raja, Gabriele Dammone, Sonia Karaz, José L. Sánchez-García, Sylviane Metairon, Guillaume Jacot, C. Florian Bentzinger, Jérôme N. Feige, Pascal Stuelsatz
Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells
Auteurs et autrices
Laiyen Garcia Delgado, Amélie Derome, Samantha Longpré, Marilyne Giroux-Dansereau, Ghenwa Basbous, Christine Lavoie, Caroline Saucier, Jean-Bernard Denault
Whole blood multiplex measurements using electrochemical aptamer-based biosensors
Discovery of a CCR2-targeting pepducin therapy for chronic pain
Auteurs et autrices
Élora Midavaine, Rebecca L Brouillette, Elizabeth Théberge, Christine E Mona, Sakeen W Kashem, Jérôme Côté, Vera Zeugin, Élie Besserer-Offroy, Jean-Michel Longpré, Éric Marsault, Philippe Sarret
Mitotic deacetylase complex (MiDAC) recognizes the HIV-1 core promoter to control activated viral gene expression
Auteurs et autrices
Emmanuelle Wilhelm, Mikaël Poirier, Morgane Da Rocha, Mikaël Bédard, Patrick P McDonald, Pierre Lavigne, Christie L Hunter, Brendan Bell
Dopamine-sensitive neurons in the mesencephalic locomotor region control locomotion initiation, stop, and turns
Auteurs et autrices
Andrea Juárez Tello, Cornelis Immanuel van der Zouwen, Léonie Dejas, Juan Duque-Yate, Joël Boutin, Katherine Medina-Ortiz, Jacinthlyn Sylvia Suresh, Jordan Swiegers, Philippe Sarret, Dimitri Ryczko
Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antivirals
Auteurs et autrices
Jimena Pérez-Vargas, Gabriel Lemieux, Connor A.H. Thompson, Antoine Désilets, Siobhan Ennis, Guang Gao, Danielle G. Gordon, Annika Lea Schulz, Masahiro Niikura, Ivan Robert Nabi, Mel Krajden, Pierre-Luc Boudreault, Richard Leduc, François Jean
Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice
Auteurs et autrices
Emmeran Le Moal †, Yuguo Liu ‡, Jasmin Collerette-Tremblay ‡, Simon Dumontier, Paul Fabre, Thomas Molina, Junio Dort §, Zakaria Orfi, Nicolas Denault, Joël Boutin, Joris Michaud, Hugo Giguère, Alexandre Desroches, Kien Trân, Benjamin Ellezam, François Vézina, Sonia Bedard, Catherine Raynaud, Frederic Balg, Philippe Sarret, Pierre- Luc Boudreault, Michelle S. Scott, Jean- Bernard Denault, Eric Marsault †, Jerome N. Feige, Mannix Auger- Messier, Nicolas A. Dumont, C. Florian Bentzinger
Motivation to participate and attrition factors in a COVID-19 biobank: A qualitative study
Auteurs et autrices
Laura Jalbert, Anne-Sophie Hautin, Marie Baron, Ève Dubé, Myriam Gagné, Catherine Girard, Catherine Larochelle, Annie LeBlanc, Maxime Sasseville, Simon Décary, Karine Tremblay
Galectin-8 modulates human osteoclast activity partly through isoform-specific interactions
Auteurs et autrices
Michèle Roy, Léopold Mbous Nguimbus, Papa Yaya Badiane, Victor Goguen-Couture, Jade Degrandmaison, Jean-Luc Parent, Marie A Brunet, Sophie Roux
A recurrent de novo MAX p.Arg60Gln variant causes a syndromic overgrowth disorder through differential expression of c-Myc target genes
Auteurs et autrices
Erica L. Harris, Vincent Roy, Martin Montagne, Ailsa M.S. Rose, Helen Livesey, Margot R.F. Reijnders, Emma Hobson, Francis H. Sansbury, Marjolein H. Willemsen, Rolph Pfundt, Daniel Warren, Vernon Long, Ian M. Carr, Han G. Brunner, Eamonn G. Sheridan, Helen V. Firth, Pierre Lavigne, James A. Poulter
Moving towards the implementation of pharmacogenetic testing in Quebec
Auteurs et autrices
Ling Jing Li, Samuel Legeay, Ann-Lorie Gagnon, Marie-Pier Frigon, Laurence Tessier, Karine Tremblay