Épisode 28 : Étude DAPA-HF
Efficacité de la dapagliflozine chez les sujets avec insuffisance cardiaque à fraction d’éjection diminuée (étude DAPA-HF)
Diffusé le 17 octobre 2019
Dans cette 28e baladodiffusion, les Drs Luc Lanthier et et Charles Dussault discutent de l’efficacité de la dapagliflozine (Forxiga®), un inhibiteur des SGLT2, chez les sujets avec insuffisance cardiaque à fraction d’éjection diminuée avec l’étude DAPA-HF, en plus de réviser la littérature médicale de septembre 2019.
Référence principale
McMurray JJV, Solomon SD, Inzucchi SE, Kober L, Kosiborod MN, Martinez FA, et al. Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction. N Engl J Med. 2019;381(21):1995-2008. PubMed PMID: 31535829.
Article résumé
Lanthier L, Dussault C, Huard G, Plourde MÉ, Cauchon M. Chez les sujets avec insuffisance cardiaque à fraction d’éjection diminuée avec ou sans diabète de type 2, est-ce que la dapagliflozine, un inhibiteur des SGLT2, est efficace pour prévenir l’insuffisance cardiaque décompensée ou la mortalité cardiovasculaire tout en étant sécuritaire ? Rev Med Interne. 2020;41(2):143-144. PubMed PMID: 31928796
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