Épisode 9 : Étude CANVAS
Efficacité cardiovasculaire et rénale de la canagliflozine dans le diabète type 2 (étude CANVAS)
Diffusé le 22 juillet 2017
Dans cette neuvième baladodiffusion, le Dr Luc Lanthier discute de l’effet de la canagliflozine, un antihyperglycémiant de la classe des inhibiteurs des SGLT2, dans le traitement des patients diabétiques de type 2 à risque cardiovasculaire élevé, en plus de réviser la littérature médicale de juin 2017.
Référence principale
Neal B, Perkovic V, Mahaffey KW, de Zeeuw D, Fulcher G, Erondu N, et al. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. N Engl J Med. 2017 Aug 17;377(7):644-657. PubMed PMID: 28605608.
Articles associés
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE; EMPA-REG OUTCOME Investigators. Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med. 2015;373(22):2117-28. PMID: 26378978
Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB; LEADER Steering Committee; LEADER Trial Investigators. Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med. 2016;375(4):311-22. PubMed PMID : 27295427
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Guides de pratique récents
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Référence du quiz clinique
Winkelman JW, Armstrong MJ, Allen RP, Chaudhuri KR, Ondo W, Trenkwalder C, Zee PC, Gronseth GS, Gloss D, Zesiewicz T. Practice guideline summary: Treatment of restless legs syndrome in adults: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2016;87(24):2585-2593. PMID: 27856776