Philippe Dauphin Ducharme
Professeur, Faculté des sciences
FAC. SCIENCES Chimie
Présentation
Sujet de recherche
Electrochemical Systems, Nanosystems, Biotechnology
Disciplines de recherche
Chemistry
Mots-clés
Biosensors, DNA, Electrochemistry, Biophysics, Corrosion, Supramolecular Chemistry, Inorganic Synthesis, Pharmacology
Intérêts de recherche
Biosensors / DNA / Proteins / Electrochemistry / Real-time Detection / Point-of-Care / Pharmacokinetics / Supramolecular Chemistry / Corrosion / Materials Chemistry / Inorganic Synthesis
Langues parlées et écrites
Anglais, Français
Diplômes
(2015). SECM Study of Mg Alloys to Develop Anti-Corrosion Mechanism for Industrial Applications (Doctorate, Ph.D. in Chemistry). McGill University.
(2011). (Bachelor's, Baccalauréat en Chimie). Université de Montréal.
Expérience académique
Assistant Professor. (2020-). Université de Sherbrooke. Canada.
Post-doctoral Fellow. (2015-2019). University of California, Santa Barbara. United States of America.
Ph.D. Candidate. (2011-2015). McGill University. Canada.
Teaching Assistant for the Organic Chemistry I laboratory. (2012-2012). McGill University. Canada.
JCEMolChem Intern. (2011-2011). Université de Paris VI (P & M Curie). France.
NSERC Summer Internship. (2010-2010). Université de Montréal. Canada.
NSERC Summer Internship. (2009-2009). Université du Québec à Montréal. Canada.
Summer Internship. (2007-2007). Université du Québec à Montréal. Canada.
Prix et distinctions
- (2018) Postdoctoral Fellowship. Natural Sciences and Engineering Research Council of Canada (NSERC). (Prize / Award).
- (2017) Postdoctoral research scholarship (B3). Fonds de recherche du Québec - Nature et technologies (FRQNT). (Prize / Award).
- (2015) Bourses de doctorat en recherche (B2). Fonds de recherche du Québec - Nature et technologies (FRQNT). (Prize / Award).
- (2015) NSERC Postgraduate Scholarships-Doctoral Program. Natural Sciences and Engineering Research Council of Canada (NSERC). (Prize / Award).
- (2013) 2nd Best Poster. Electrochemical Society of Canada. (Prize / Award).
- (2013) Bourses de mai?trise en recherche (B1). Fonds de recherche du Québec - Nature et technologies (FRQNT). (Prize / Award).
- (2013) Edward G. Weston Award. Electrochemical Society. (Prize / Award).
- (2013) Research Mobility Award. McGill University. (Prize / Award).
- (2012) 2nd Best Poster. NACE. (Prize / Award).
- (2011) Bourse Lucien Piché. Lucien Piché. (Prize / Award).
- (2011) Bourse de Prestige. Université de Montréal. (Prize / Award).
- (2011) Bourse JCEMolChem. JCEMolChem. (Prize / Award).
- (2010) Best Undergraduate Poster. SACIQ. (Prize / Award).
- 2nd Best Thesis in 180s. Centre Québecois sur les Matériaux Fonctionnels. (Prize / Award).
- Best Oral Presentation. Canadian Society of Chemistry. (Prize / Award).
- ISE Young Electrochemist Travel Award. International Society of Electrochemistry. (Prize / Award).
- J. E. Griffiths Award. McGill University. (Prize / Award).
- Pall Dissertation Award. McGill University. (Prize / Award).
- Plaque des Industries Chimiques. Société des Industries Chimiques. (Prize / Award).
- Prix Recherche et Création. Université de Sherbrooke. (Prize / Award).
Financement
- Grant. (Awarded). Co-applicant. Cross-disciplinary Acuity Training Program in Intelligent and Responsible Drug Discovery. Natural Sciences and Engineering Research Council of Canada (NSERC). Collaborative Research and Training Experience program. 1 650 000 $. (2023-2029)
- Grant. (Awarded). Principal Investigator. Biocapteurs électrochimiques à base d’ADN pour la multidétection de molécules dans des matrices complexes non-diluées. Axelys. Bioprocédés et bioproduction. 275 700 $. (2025-2028)
- Grant. (Awarded). Principal Investigator. Plateforme de biocapteurs pour le suivi pharmacocinétique de molécules psychoactives. Fonds de recherche du Québec - Santé (FRQS). Chercheurs-boursiers J1. 357 526 $. (2024-2028)
- Grant. (Under Review). Principal Applicant. Multi-détection d'anesthésiques dans des matrices complexes à l'aide de biocapteurs électrochimiques. Fonds de recherche du Québec - Nature et technologies (FRQNT). NOVA. 275 000 $. (2025-2028)
- Grant. (Under Review). Co-investigator. CRxEA. Canada Foundation for Innovation (CFI). Innovation Fund. 7 112 277 $. (2025-2026)
- Grant. (Awarded). Principal Applicant. Biocapteurs électrochimiques à base d'aptamères pour la détection d'anesthésiants. Fonds de recherche du Québec - Nature et technologies (FRQNT). NOVA. 275 000 $. (2022-2025)
- Grant. (Awarded). Co-applicant. The Acuity-Qc consortium: predicting and imaging drug action. Ministère de l'Économie et de l'Innovation - Fonds d’accélération des collaborations en santé. 27 090 852 $. (2021-2024)
- Grant. (Completed). Principal Investigator. Infrastructure for the Development of Electrochemical Biosensors. Canada Foundation for Innovation (CFI). Ministère de l'Économie et de l'Innovation du Québec. John R. Evans Leaders Fund. 130 000 $. (2021-2023)
- Grant. (Completed). Principal Investigator. Electrochemical Aptamer-Based Biosensors for Salivary Molecular Measurements. Natural Sciences and Engineering Research Council of Canada (NSERC). Alliance. 50 000 $. (2022-2023)
- Grant. (Completed). Principal Investigator. Biophysique d'oligonucléotides sur des électrodes pour le développement de biocapteurs électrochimiques. Fonds de recherche du Québec - Nature et technologies (FRQNT). Relève Professorale. 110 000 $. (2021-2023)
- Grant. (Awarded). Principal Investigator. Start-up fund. Université de Sherbrooke. Start-up for new professors. 50 000 $. (2020-2023)
- Grant. (Completed). Principal Applicant. Advanced electrochemical workstation for the characterization of biosensors, advanced materials and environmental samples. Natural Sciences and Engineering Research Council of Canada (NSERC). Research Tools and Instruments. 149 500 $. (2021-2022)
- Grant. (Completed). Co-applicant. Intégrer les données d’approches « omiques » et d’ergocycles connectés pour une prise en charge optimisée et personnalisée des aînés en milieu clinique: Une preuve de concept du consortium iDOSE. Centre de recherche sur le viellissement de l'université de Sherbrooke. Programme de subvention interne - Initiatives Stratégiques. 20 000 $. (2021-2022)
- Grant. (Completed). Principal Investigator. Programme d'appariement du financement à la recherche. Centre de Recherche du Centre Hospitalier de l'Université de Sherbrooke Inc. (CRCHUS) (Sherbrooke, QC). Programme d'appariement. 30 000 $. (2020-2021)
- Grant. (Completed). Principal Investigator. Appui Axe Inflammation Douleur. Centre de Recherche du Centre Hospitalier de l'Université de Sherbrooke Inc. (CRCHUS) (Sherbrooke, QC). 10 400 $. (2020-2021)
- Fellowship. (Completed). Principal Investigator. PDF - NSERC. Natural Sciences and Engineering Research Council of Canada (NSERC). 90 000 $. (2016-2018)
- Fellowship. (Completed). Principal Investigator. Postdoctoral research scholarship (B3). Fonds Québécois de la Recherche sur la Nature et les Technologies (FQRNT). 70 000 $. (2015-2016)
- Scholarship. (Declined). Principal Applicant. Doctoral Research Scholarships (B2). Fonds de recherche du Québec - Nature et technologies (FRQNT). Bourses de doctorat en recherche (B2). 60 000 $. (2013-2015)
- Scholarship. (Completed). Principal Investigator. PGSD - NSERC. Natural Sciences and Engineering Research Council of Canada (NSERC). Bourse d’études supérieures du CRSNG – doctorat. 63 000 $. (2013-2015)
- Scholarship. (Completed). Principal Applicant. Master's Research Scholarships (B1). Fonds de recherche du Québec - Nature et technologies (FRQNT). Bourses de maîtrise en recherche (B1). 30 000 $. (2011-2013)
- Scholarship. (Completed). Principal Applicant. CGSM - NSERC. Natural Sciences and Engineering Research Council of Canada (NSERC). Bourse d’études supérieures du Canada au niveau de la maîtrise. 17 500 $. (2011-2012)
- Scholarship. (Completed). Principal Applicant. Undergraduate Student Research Awards - NSERC. Natural Sciences and Engineering Research Council of Canada (NSERC). Bourse de recherche de 1er cycle. 4 500 $. (2010)
- Scholarship. (Completed). Principal Applicant. Undergraduate Student Research Awards - NSERC. Natural Sciences and Engineering Research Council of Canada (NSERC). Bourse de recherche de 1er cycle. 4 500 $. (2009)
Publications
Articles de revue
- Gerson, J., Erdal, M., Dauphin-Ducharme, P., Idili, A., Hespanha, J., Plaxco, K. W., Kippin, T. A. (2024). A high-precision view of intercompartmental drug transport via simultaneous, seconds-resolved, in situ measurements in the vein and brain. British Journal of Pharmacology 181 (20), 3869-3885. (Published).
- Boivin, L.; d'Astous, E. V.; Schlachter, A.; Fortin, D.; Karsenti, P.-L.; Lescop, C.; Dauphin Ducharme, P.; Harvey, P. (2024). From a Simple Push-Pull Dye to a Functional Material by Assembly with CuBr. Journal of Materials Chemistry C (Published).
- Kaiyum, Y. A., Chao, H. P., Nguyen, M.-D., Mackereth, C. D., Dauphin Ducharme, P., Johnson, P. E. (2024). Ligand-Induced Folding in a Dopamine-Binding DNA Aptamer. ChemBioChem (Accepted).
- Jeon, B.-J., Guareschi, M. M., Stewart, J. M., Wu, E., Gopinath, A., Arroyo-Currás, N., Dauphin-Ducharme, P., Lukeman, P. S., Plaxco, K. W., Rothemund, P. W. K. (2024). Modular DNA origami-based electrochemical detection of DNA and proteins. Proceedings of the National Academy of Sciences (Accepted).
- Eisen, S. R., Dauphin-Ducharme, P., Johnson, P. E. (2024). Solution-based biophysical characterization of conformation change in structure-switching aptamers. Quarterly Reviews of Biophysics 57 e9. (Published).
- Nguyen, M.-D., Prevot, G. T., Fontaine, N., Dauphin Ducharme, P. (2024). Whole Blood Theophylline Measurements Using An Electrochemical DNA Aptamer-based Biosensor. ECS Sensors Plus 3 (3), 030601. (Published).
- d’Astous, É., Dauphin Ducharme, P. (2024). Whole blood multiplex measurements using electrochemical aptamer-based biosensors. Chemical Communications 60 6419 – 6422. (Published).
- Minh-Dat Nguyen, Meghan T. Osborne, Guy Terence Prevot, Zachary R. Churcher, Philip E. Johnson, Lena Simine, Philippe Dauphin-Ducharme. (2024). in silico Truncations and Docking to Enhance the Analytical Response of Aptamer-Based Biosensors. Biosensors Bioelectronics 265 116680. (Published).
- Deflandre, L., Dauphin-Ducharme, P. (2024). “Binding” or “Binding and switching”? A perspective on resolving conformational changes of surface-attached biomolecular receptors. ACS Sensors (Accepted).
- N. Fontaine, P. Dauphin-Ducharme. (2023). Confounding Effects on Electrochemical Aptamer-based Biosensors Response. Current Opinion in Electrochemistry 41 101361. (Published).
- É. d'Astous and P. Dauphin-Ducharme. (2023). DNA Chimeras as Electrochemical Biosensors for Host-Guest Measurements in Blood. Chemistry - A European Journal 29 (70), e202302780. (Published).
- M.-D. Nguyen, K.-N. Nguyen, S. Malo, I. Banerjee, D. Wu, L. Du-Thumm, P. Dauphin-Ducharme. (2023). Electrochemical Aptamer-Based Biosensors for Measurements in Undiluted Human Saliva. ACS Sensors 8 (12), 4625-4635. (Published).
- Erfan Rahbarimehr*, Hoi Pui Chao, Zachary R. Churcher, Sladjana Slavkovic, Yunus A. Kaiyum, Philip E. Johnson, Philippe Dauphin-Ducharme. (2023). Finding the lost dissociation constant of electrochemical aptamer-based biosensors. Analytical Chemistry 95 (4), 2229–2237. (Published).
- J. Gerson, M. K. Erdal, M. H. McDonough, K. L. Ploense, P. Dauphin-Ducharme, K. Honeywell, K. Leung, N. Arroyo-Curras, J. Gibson, W. Meiring, J. Hespanha, K. W. Plaxco and T. E. Kippin. (2023). High-precision monitoring of and feedback control over drug concentrations in the brains of freely-moving rats. Science Advances 9 (20), eadg3254. (Published).
- V. Charron-Lamoureux, L. Haroune, M Pomerleau, L. Hall, F. Orban, J. Leroux, A. Rizzi, J.-S. Bourassa, N. Fontaine, É. V. d'Astous, P. Dauphin-Ducharme, C. Y. Legault , J.-P. Bellenger, P. Beauregard. (2023). Pulcherriminic acid modulates ironavailability and protects against oxidativestress during microbial interactions. Nature Communications 14 2536. (Published).
- P. Dauphin-Ducharme*, Z. R. Churcher, A. A. Shoara, E. Rahbarimehr, S. Slavkovic, N. Fontaine, O. Boisvert, P. E. Johnson*. (2023). Redox Reporter- Ligand Competition to Support Signaling in the Cocaine- Binding Electrochemical Aptamer-Based Biosensor. Chemistry - A European Journal e202300618. (Published).
- d'Astous, E.*, Dauphin-Ducharme, P. (2022). Harnessing host–guest chemistry for electrochemical sensing in complex matrices. Current Opinion in Electrochemistry 34 101029. (Published).
- Netzahualcoyotl Arroyo-Currás, Philippe Dauphin Ducharme, P., Karen Scida, Jose L. Chávez. (2020). From the Beaker to the Body: Translational Challenges for Electrochemical, Aptamer-Based Sensors. Analytical Methods 12 1288-1310. DOI. (Published).
- Lessard, J., Dauphin Ducharme, P., Mauzeroll, J. (2020). Preface—JES Focus Issue on Organic and Inorganic Molecular Electrochemistry. Journal of the Electrochemical Society 167 150001. (Published).
- Alex M. Downs, Julian Gerson, Kyle L. Ploense, Kevin W. Plaxco, Philippe Dauphin Ducharme. (2020). Sub-second-resolved Molecular Measurements Using Electrochemical Phase Interrogation of Aptamer-Based Sensors. Analytical Chemistry 92 (20), 14063-14068. (Published).
- Philippe Dauphin Ducharme, Kyungae Yang, Netzahualcoyotl Arroyo-Currás, Kyle L. Ploense, Yameng Zhang, Julian Gerson, Martin Kurnik, Tod E. Kippin, Milan N. Stojanovic, Kevin W. Plaxco. (2019). Electrochemical Aptamer-based Sensors for Improved Therapeutic Drug Monitoring and High-Precision, Feedback-controlled Drug Delivery. ACS Sensors 4 (10), 2832-2837. DOI. (Published).
- Philippe Dauphin Ducharme, Netzahualcoyotl Arroyo-Currás, Kevin W. Plaxco. (2019). High-precision electrochemical measurements of the guanine-, mismatch- and length-dependence of electron transfer in surface-attached DNA are consistent with a contact-mediated mechanism. Journal of the American Chemical Society 141 1304-1311. DOI. (Published).
- Gabriel Ortega, Martin Kurnik, Philippe Dauphin Ducharme, Hui Li, Netzahualcoyotl Arroyo-Currás, Amanda Caceres, Kevin W. Plaxco. (2019). Surface attachment enhances the thermodynamic stability of protein L. Angewandte Chemie – International Edition 58 1714-1718. DOI. (Published).
- Netzahualcoyotl Arroyo-Currás, Philippe Dauphin Ducharme, Gabriel Ortega, Kyle L. Ploense, Tod E. Kippin, Kevin W. Plaxco. (2018). **COVER** Subsecond-Resolved Molecular Measurements in the Living Body Using Chronoamperometrically Interrogated Aptamer-Based Sensors **COVER**. ACS Sensors 3 360-366. DOI. (Published).
- Philippe Dauphin Ducharme, Netzahualcoyotl Arroyo-Currás, Ramesh Adhikari, Jacob Somerson, Gabriel Ortega, Dmitrii E. Makarov, Kevin W. Plaxco. (2018). Chains Dynamics Limit Electron Transfer from Electrode-Bound, Single-Stranded Oligonucleotides. Journal of Physical Chemistry C 122 21441-21448. DOI. (Published).
- Martin Kurnik, Gabriel Ortega, Philippe Dauphin Ducharme, Hui Li, Amanda Caceres, Kevin W. Plaxco. (2018). Quantitative measurements of protein-surface interaction thermodynamics. Proceedings of the National Academy of Sciences of the United States of America 115 8352-8357. DOI. (Published).
- Hui Li, Philippe Dauphin Ducharme, Gabriel Ortega, Kevin W. Plaxco. (2017). **ACS Select** Calibration-free electrochemical biosensors supporting accurate molecular measurements directly in undiluted whole blood **ACS Select**. Journal of the American Chemical Society 139 11207-11213. DOI. (Published).
- Hui Li, Philippe Dauphin Ducharme, Netzahualcoyotl Arroyo-Currás, Claire Tran, Philip A. Vieira, Shaoguang Li, Christina Shin, Jacob Somerson, Tod E. Kippin, Kevin W. Plaxco. (2017). **VIP** A biomimetic phosphatidylcholine-terminated monolayer greatly improves the in-vivo performance of electrochemical aptamer-based sensors **VIP**. Angewandte Chemie – International Edition 129 7600-7603. DOI. (Published).
- Philippe Dauphin Ducharme, Netzahualcoyotl Arroyo-Currás, Martin Kurnik, Gabriel Ortega, Hui Li, Kevin W. Plaxco. (2017). A Simulation-Based Approach to Determining Electron Transfer Rates using Square-Wave Voltammetry. Langmuir 33 4407-4413. DOI. (Published).
- David Polcari, Philippe Dauphin Ducharme, Janine Mauzeroll. (2016). **COVER** Scanning Electrochemical Microscopy: A Comprehensive Review of Experimental Parameters from 1989-Present. **COVER**. Chemical Reviews 116 13234-13278. DOI. (Published).
- Philippe Dauphin Ducharme, Kevin W. Plaxco. (2016). Maximizing the Signal Gain of Electrochemical-DNA Sensors. Analytical Chemistry 88 11654-11662. DOI. (Published).
- Philippe Dauphin-Ducharme, Janine Mauzeroll. (2015). **COVER** Surface Analytical Methods Applied to Magnesium Corrosion **COVER**. Analytical Chemistry 87 7499-7509. DOI. (Published).
- Philippe Dauphin-Ducharme, Christian Kuss, David Rossouw, Nicholas A. Payne, Laurence Danis, Gianluigi A. Botton, Janine Mauzeroll. (2015). Corrosion Product Formation Monitored Using the Feedback Mode of Scanning Electrochemical Microscopy with Carbon Microelectrodes. Journal of the Electrochemical Society 162 (12), C677-C683. DOI. (Published).
- Philippe Dauphin-Ducharme, W. Jeffrey Binns, Michael E. Snowden, David W. Shoesmith, Janine Mauzeroll. (2015). Determination of the local corrosion rate of magnesium alloys using a shear force mounted scanning microcapillary method. Faraday Discussion 180 331-345. DOI. (Published).
- Philippe Dauphin-Ducharme, R. Matthew Asmussen, David W. Shoesmith, Janine Mauzeroll. (2015). In-situ Mg2+ release monitored during magnesium alloy corrosion. Journal of Electroanalytical Chemistry 736 61-68. DOI. (Published).
- Ushula Mengesha Tefashe, Philippe Dauphin-Ducharme, Mohsen Danaie, Zach P. Cano, Joey R. Kish, Gianluigi A. Botton, Janine Mauzeroll. (2015). Localized Corrosion Behavior of AZ31B Magnesium Alloy with an Electrodeposited Poly(3,4-Ethylenedioxythiophene) Coating. Journal of the Electrochemical Society 162 C536-C544. DOI. (Published).
- Philippe Dauphin-Ducharme, Fiora Rosati, Andrea Greschner, A. Dowine De Bruijn, Danielle Salvatore, Violeta Toader, Kai Lin Lau, Janine Mauzeroll and Hanadi Sleiman. (2015). Modulation of Charge Transport Across Double-Stranded DNA by the Site-Specific Incorporation of Copper Bis-Phenanthroline Complexes. Langmuir 31 1850-1854. DOI. (Published).
- R. Matthew Asmussen, W. Jeffrey Binns, Pellumb Jakupi, Philippe Dauphin-Ducharme, Ushula M. Tefashe, Janine Mauzeroll, David Shoesmith. (2015). Reducing the corrosion rate of magnesium alloys using ethylene glycol for advanced electrochemical imaging. Corrosion Science 93 70-79. DOI. (Published).
- Amlan K. Pal, Philippe Dauphin-Ducharme, Garry S. Hanan. (2014). Enhanced stereoselectivity in a di-Ru(II) complex of an achiral bis-bidentate ligand. Chemical Communications 50 (25), 3303-3305. DOI. (Published).
- Nicolas Cottenye, Gustavo Carbajal, Zhong-Kai Cui, Philippe Dauphin-Ducharme, Janine Mauzeroll, Michel Lafleur. (2014). Formation, stability, and pH sensitivity of free-floating, giant unilamellar vesicles using palmitic acid–cholesterol mixtures. Soft Matter 10 6451-6456. DOI. (Published).
- Philippe Dauphin-Ducharme, R. Matthew Asmussen, Ushula M. Tefashe, Mohsen Danaie, W. Jeffrey Binns, Pellumb Jakupi, Gianluigi A. Botton, David W. Shoesmith and Janine Mauzeroll. (2014). Local Hydrogen Fluxes Correlated to Microstructural Features of a Corroding Sand Cast AM50 Magnesium Alloy. Journal of the Electrochemical Society 161 C557-C564. DOI. (Published).
- Ushula Mengesha Tefashe, Michael Edward Snowden, Philippe Dauphin-Ducharme, Mohsen Danaie, Gianluigi A. Botton, Janine Mauzeroll. (2014). Local flux of hydrogen from magnesium alloy corrosion investigated by scanning electrochemical microscopy. Journal of Electroanalytical Chemistry 720-721 121-127. DOI. (Published).
- Dao Trinh, Philippe Dauphin-Ducharme, Ushula Mengesha Tefashe, Joseph R. Kish, and Janine Mauzeroll. (2012). Influence of Edge Effects on Local Corrosion Rate of Magnesium Alloy/Mild Steel Galvanic Couple. Analytical Chemistry 84 9899-9906. DOI. (Published).
- Samik Nag, Janaina G. Ferreira, Ludwig Chenneberg, Philippe Dauphin-Ducharme, Garry S. Hanan, Giuseppina La Ganga, Scolastica Serroni, Sebastiano Campagna. (2010). Changing the Role of 2,2'-Bipyridine from Secondary Ligand to Protagonist in [Ru(bpy)2(N-N)]2+ Complexes: Low-Energy, Red Emission from a Ruthenium(II)-to-2,2'-Bipyridine 3MLCT State. Inorganic Chemistry 50 7-9. DOI. (Published).
Livres
- Dauphin Ducharme, P., Ploense, K. L., Arroyo-Currás, N., Kippin, T. E., Plaxco, K. W. (2022). Biomedical Engineering Technologies. Springer. (Published).
Articles de magazine
- Philippe Dauphin-Ducharme. (2013). Assessment of magnesium alloy corrosion using potentiometric mode of scanning electrochemical microscopy. Electrochemical Society Interface. 22(4). 83-84.
Rapports
- Dauphin-Ducharme, P., Binns, W. J., Shoesmith, D. W. and Mauzeroll, J. (2015). Determination of the Local Corrosion Rate of Magnesium Alloys using a Shear Force Mounted Scanning Microcapillary Method. General Motors. 19 p.
- Tefashe, U. M., Dauphin-Ducharme, P., Danaie, M., Cano, Z. P., Kish, J. R., Botton, G. A., Mauzeroll, J. (2015). Localized Corrosion Behavior of AZ31B Mg Alloy with a PEDOT Coating. General Motors. 35 p.
- Dauphin-Ducharme, P., Asmussen, R. M., Tefashe, U. M., Danaie, M., Binns, J., Jakupi, P., Botton, G. A., Shoesmith, D. W. and Mauzeroll, J. (2014). Microgalvanic Corrosion of Sand Cast AM50 Mg Alloy Assessed using the Substrate-Generation / Tip-Collection Mode of SECM. General Motors. 23 p.
- Dauphin-Ducharme, P., Snowden, M. E., Mauzeroll, J. (2014). Shear Force Controlled Scanning Micropipet for High Resolution Topographic Imaging. General Motors. 13 p.
- Tefashe, U. M., Dauphin-Ducharme, P., Mauzeroll, J. (2014). Study of the Local Electrodeposition of PEDOT on AZ31 Alloy in Ionic Liquid and Corrosion Behavior of the Coated Alloy. General Motors. 18 p.
- Tefashe, U. M., Snowden, M. E., Dauphin-Ducharme, P., Danaie, M., Botton, G. A., Mauzeroll, J. (2013). (2013). Local Rate of Hydrogen Evolution from Magnesium Alloy Corrosion Investigated by SECM. General Motors. 20 p.
- Dauphin-Ducharme, P., Tefashe, U. M., Trinh, D., Kish, J., Mauzeroll, J. (2012). Influence of Edge Effects on Local Corrosion Rate of Magnesium Alloy/Mild Steel Galvanic Couple. General Motors. 21 p.
- Tefashe, U. M., Dauphin-Ducharme, P., Mauzeroll, J. (2012). Influence of Microstructure on Local Corrosion Properties of AM50 Magnesium Alloys Studied by Scanning Electrochemical Microscopy. General Motors. 15 p.
- Dauphin-Ducharme, P., Mauzeroll, J. (2011). Simulation (2D) of corrosion at bi-metallic interfaces: UQÀM Validation report on existing GM model to 4.2 COMSOL version. General Motors. 20 p.
Articles de conférence
- Ushula Mengesha Tefashe, Philippe Dauphin-Ducharme, Michael E. Snowden, Janine Mauzeroll. (2013). Correlation between microstructure and corrosion properties of die-cast AM50 magnesium alloy. Magnesium Technology, 1567-1573. (Published).
- Philippe Dauphin-Ducharme, Janine Mauzeroll. (2013). Monitoring magnesium cation release dynamics during magnesium alloy corrosion using potentiometric Mg2+ ion-selective microelectrode. Magnesium Technology, 1470-1471. (Published).
- Dao Trinh, Philippe Dauphin-Ducharme, Ushula Mengesha Tefashe, Joseph R. Kish, Janine Mauzeroll. (2013). Studying magnesium alloys using scanning electrochemical microscopy. Magnesium Technology, 1472-1473. (Published).
Propriétés intellectuelles
Patents
- Hui Li, Philippe Dauphin Ducharme, Gabriel Ortega, Kevin W. Plaxco. (2024). Calibration-free Electrochemical Biosensors. US 62/513,796. United States of America. (Allowed).
- Dauphin-Ducharme, Philippe; Nguyen, M.-D., Banerjee, I., Wu, D., Du-Thumm, L. Electrochemical Aptamer-based Biosensors for Salivary Molecular Measurements of a Biomarker. 63/375,802. United States of America. (Pending).
- Dauphin Ducharme, P., d'Astous, É. V. Electrochemical Multiplex Biosensors. US 63/570,922. United States of America. (Pending).
- Mauzeroll, J.; Noyhouzer, T. A.; Snowden, M. E.; Dauphin Ducharme, P.; Mazurkiewicz, S.; L'homme, C.; Desjardins, S.; Canesi, S. Redox Triggered Vesicles. US 62/105,039. United States of America. (Granted/Issued).
Autres contributions
Cours enseignés
- Organic Chemistry I. CHEM 211. (2012-01-10 à 2012-04-13).
Gestion d'évènements
- Symposium organiser. (2024) 75th International Society of Electrochemistry. (Conference).
- Organizer. (2023) The McGill Molecular Science Mini-Meeting. (Workshop).
- Session Chair. (2022) Canadian Chemistry Conference and Exhibition 2022. (Conference).
- Chair. (2015) 5th Montreal ECS Student Chapter Symposium. (Conference).
- Chair. (2014) 4th Montreal ECS Student Chapter Symposium. (Conference).
- Vice-Chair. (2013-2014) 3rd Montreal ECS Student Chapter Symposium. (Conference).
Présentations
- Nguyen, M.-D. (2024). Aptamer Translation from SELEX to Surface for Molecular Measurements in Complex Matrices. Canadian Society of Chemistry Conference. Winnipeg, Canada
- Fontaine, N. (2024). Comparison of the Analytical Performances of DNA-based Interfaces Through Electrochemical-Surface Plasmon Resonance. Bioanalytical Sensors – Gordon Research Seminar and Gordon Research Conference. Newport, United States of America
- Fontaine, N. (2024). Comparison of the Analytical Performances of DNA-based Interfaces Through Electrochemical-Surface Plasmon Resonance. 75th International Society of Electrochemistry Meeting. Montreal, Canada
- Nguyen, M.-D. (2024). Computational Molecular Docking to Guide Development of Electrochemical Aptamer-based Biosensors. 75th International Society of Electrochemistry Meeting. Montreal, Canada
- Deflandre, L. (2024). Development of Electrochemical Aptamer-Based Micro-biosensors for Neurotransmitter Quantification and Imaging. 75th International Society of Electrochemistry Meeting. Montreal, Canada
- (2024). Electrochemical Aptamer-based Biosensors for Multiplexed Measurements in Saliva. Canadian Society of Canada (CSC) National Meeting. Winnipeg, Canada
- (2024). Electrochemical Biosensors for Multiplexed Whole Blood Measurements. 75th International Society of Electrochemistry Meeting. Montreal, Canada
- (2024). Electrochemical Biosensors for Personnalized Medicine Applications. Canada's Rising Stars in Electrochemical Systems Symposium. Canada
- d'Astous, É. V. (2024). Generalization of Electrochemical DNA-Host Chimeras for Continuous Host-Guest Sensing in Undiluted Whole Blood. 75th Annual Meeting of the International Society of Electrochemistry. Montreal, Canada
- Corriveau, T. (2024). Harnessing electrochemical biosensors for continuous drug monitoring at the point of care. Canadian Conference on Electrical and Computer Engineering. Kingston, Canada
- Corcoran, N. (2024). Interrogation multifréquentielle de biocapteurs électrochimiques à base d’aptamères. 34e Colloque de chimie de l’Université de Sherbrooke. Sherbrooke, Canada
- Fontaine, N. (2024). Les capteurs électrochimiques à base d’ADN : la solution pour le suivi continu de cibles thérapeutiques dans le corps. 11e colloque sciences et culture. Mont-Tremblant, Canada
- Corcoran, N. (2024). Multi-Frequency Interrogation of Electrochemical Aptamer-Based Biosensors. 75th International Society of Electrochemistry Meeting. Montreal, Canada
- (2024). Nucleic Acids Electrochemical Biosensors for Point-of-care Measurements. McGill - Chemical Society Lecture. Montreal, Canada
- Nguyen, M.-D. (2024). SELEX to Sensors: A Step-by-Step Guide for Translating Aptamers. 75th International Society of Electrochemistry Meeting. Montreal, Canada
- d'Astous, É. V. (2024). Whole Blood Multiplex Measurements using Electrochemical Aptamer-Based Biosensors. Gordon Research Conference on Bioanalytical Sensors. Newport, United States of America
- (2023). Biocapteurs d’ADN pour le suivi moléculaire dans des matrices complexes et dans le corps. 7th Advanced Materials Annual Meeting. Victoriaville, Canada
- (2023). Biocapteurs d’ADN pour le suivi moléculaire dans des matrices complexes et dans le corps. Département de Biochimie et de Génomique Fonctionnelle. Sherbrooke, Canada
- d'Astous, É. (2023). Biocapteur électrochimique hôte invité pour mesure dans le sang. CAFECAUS. Sherbrooke, Canada
- Prevot, G. (2023). Computational Molecular Docking to Guide the Development of Electrochemical Aptamer-based Biosensors. 7th Advanced Materials Annual Meeting. Victoriaville, Canada
- Prevot, G. (2023). Computational Molecular Docking to Guide the Development of Electrochemical Aptamer-based Biosensors. McGill Molecular sciences mini meeting. Montreal, Canada
- (2023). Computationally-Guided Design of Electrochemical Aptamers-based Biosensors. McGill Molecular Science Mini-Meeting. Montreal, Canada
- d'Astous, É. (Best poster award). (2023). DNA Chimeras as Electrochemical Biosensors for Host-Guest Measurements in Blood. 7th Advanced Materials Annual Meeting. Victoriaville, Canada
- d'Astous, É. (2023). DNA Chimeras as Electrochemical Biosensors for Host-Guest Measurements in Blood. 7th Advanced Materials Annual Meeting. Victoriaville, Canada
- d'Astous, É. V. ***Prix du public***. (2023). DNA Chimeras as Electrochemical Biosensors for Host-Guest Measurements in Blood. Journée scientifique de l’axe inflammation-douleur. Sherbrooke, Canada
- d'Astous, É. (2023). DNA Chimeras as Electrochemical Biosensors for Host-Guest Measurements in Blood. McGill Molecular Science Mini-Meeting. Montreal, Canada
- Fontaine, N. (2023). Harnessing electrochemical biosensors for continuous drug monitoring at the point of care. Journée scientifique de l’axe inflammation-douleur. Sherbrooke, Canada
- Nguyen, M.-D. (2023). Human salivary glucose measurement using electrochemical aptamer-based biosensors. McGill Molecular Science Mini-Meeting. Montreal, Canada
- Nguyen, M.-D. (2023). Measurement of chemotherapeutic drug in artificial interstitial fluid using electrochemical aptamer-base biosensors. Annual Meeting of Quebec Centre for Advanced Materials. Victoriaville, Canada
- Nguyen, M.-D. (2023). Measurement of glucose in human saliva using electrochemical aptamer-based biosensors. International Congress on Biosensors. Busan, Korea, South
- Banerjee, I. (2023). Measurement of salivary biomarkers using aptamer based sensors. International Association for Dental, Oral, and Craniofacial Research. Bogota, Colombia
- Nguyen, M.-D. (2023). Molecular docking-assisted aptamer truncation for development of electrochemical aptamer-based biosensors. International Congress on Biosensors. Busan, Korea, South
- Rahbarimehr, E. (2023). On the Signaling Mechanism of Electrochemical Aptamer-based Biosensors. McGill Molecular Science Mini-Meeting. Montreal, Canada
- Rahbarimehr, E. (2023). On the Signaling Mechanism of Electrochemical Aptamer-based Biosensors. 7th Advanced Materials Annual Meeting. Victoriaville, Canada
- Fontaine, N. (2023). Surface Plasmon Resonance: a Tool to Facilitate Translation of Aptamers into Electrochemical Aptamer based Biosensors. 7e Colloque annuel sur la recherche des matériaux fonctionnels (CQMF). Victoriaville, Canada
- Fontaine, N. (2023). Surface Plasmon Resonance: a Tool to Facilitate Translation of Aptamers into Electrochemical Aptamer based Biosensors. McGill molecular science mini-meeting. Montreal, Canada
- (2022). Biocapteurs d’ADN pour le suivi moléculaire dans le corps. Midi-causerie du thème fédérateur Santé de l'Université de Sherbrooke. Canada
- (2022). DNA-based biosensors for molecular monitoring in the body. Montreal ECS Student Chapter Symposium. Montreal, Canada
- Rahbarimehr, E. (2022). E-AB sensors' interrogation via square wave voltammetry and electrochemical impedance spectroscopy techniques. Symposium of the ECS Montreal student chapter at University de Montreal. Montreal, Canada
- (2022). Electrochemical Host-Guest Biosensor for In Blood Measurements. The Canadian Society for Analytical Sciences and Spectroscopy. Kingston, Canada
- d'Astous, É. (2022). Electrochemical Sensing Using Host-Guest Chemistry. Bioanalytical Sciences Gordon Research Conference. Newport, United States of America
- d'Astous, É. (2022). Electrochemical Sensing Using Host-Guest Chemistry. Symposium of the ECS Montreal student chapter at University de Montreal. Montreal, Canada
- (2022). Harnessing Host-Guest Chemistry for Electrochemical Sensing. Canadian Chemistry Conference and Exhibition 2022. Calgary, Canada
- (2021). Biocapteurs d’ADN pour le suivi moléculaire. Conférence départementale du département de Biologie de l’université de Sherbrooke. Sherbrooke, Canada
- (2021). Développement de biosenseurs permettant la détection en temps réel des molécules thérapeutiques. Semaine de la culture scientifique. Sherbrooke, Canada
- Rahbarimehr, E. (2021). E-AB sensors' interrogation via square wave voltammetry and electrochemical impedance spectroscopy techniques. ECS Canada fall symposium at Trent University. Peterborough, Canada
- d'Astous, É. (2021). Electrochemical Sensing Using Host-Guest Chemistry. ECS Canada fall symposium at Trent University. Peterborough, Canada
- d'Astous, É. (2021). Electrochemical Sensing Using Host-Guest Chemistry. Colloque de chimie de l’université de Sherbrooke. Sherbrooke, Canada
- (2021). In Brain and In Vein Detection of Antibiotics using Electrochemical-DNA Biosensors. 239th Electrochemical Society Meeting. Chicago, United States of America
- (2021). In Brain and In Vein Detection of Antibiotics using Electrochemical Aptamer-based Biosensors. International Society on Aptamers. Oxford, United Kingdom
- (2021). Molecular Monitoring in the Body using Electrochemical DNA-based Biosensors. Electrochemical Society Meeting of Canada. Winnipeg, Canada
- (2021). Molecular Monitoring in the Body using Electrochemical DNA-based Biosensors. McGill Chemical Society Lecture. Montreal, Canada
- (2021). Sub-second Molecular Measurements in the Body using Electrochemical Aptamer-based Biosensors. Canadian Society of Chemistry Annual Meeting. Montreal, Canada
- (2020). In Brain and In Vein Detection of Antibiotics using Electrochemical-DNA Biosensors. Webinar at Institut Català de Nanociència i Nanotecnologia (ICN2). Barcelona, Spain
- (2019). Biosenseurs d’ADN pour la détection et livraison contrôlée d’antibiotiques in vivo. Séminaire de l'Institut de Pharmacologie de l'université de Sherbrooke. Sherbrooke, Canada
- (2019). In Vein and In Brain Detection of Drugs using DNA Biosensors. 102nd Canadian Chemistry Conference and Exhibition. Quebec, Canada
- (2019). In Vein and In Brain Detection of Drugs using DNA Biosensors. 70th Annual Meeting of the International Society of Electrochemistry. Durban, South Africa, Republic of
- (2018). Biology-Inspired Real-Time Monitoring of Drugs in the Living Body using Aptamer-Based Electrochemical Biosensors. Canadian Society of Chemistry. Edmonton, Canada
- (2018). Engineering Aptamers to Maximize their Analytical Performance using a Thermodynamic Approach Towards Real-Time Monitoring of Drugs in the Living Body. American Chemical Society National Meeting. Boston, United States of America
- (2017). Calibration-free Electrochemical DNA Biosensors. Canadian Society of Chemistry. Toronto, Canada
- (2017). Determination of Electron Transfer Rates in Self-Assembled DNA Monolayers. Canadian Society of Chemistry. Toronto, Canada
- (2015). Magnesium Alloys Corrosion Studied by Scanning Electrochemical Microscopy. Canadian Society of Chemistry. Ottawa, Canada
- (2015). New Insights into Magnesium Alloy Corrosion using Scanning Electrochemcial Microscopy. American Chemical Society National Meeting. Denver, United States of America
- (2014). New Insights in Magnesium Alloys Corrosion. Centre Québecois sur les Matériaux Fonctionnels. Shawinigan, Canada
- (2013). Monitoring Magnesium Alloys Corrosion Using Scanning Probe Techniques. Canadian Society of Chemistry. Quebec, Canada
- (2013). Monitoring Magnesium Cation Release Dynamics during Magnesium Alloy Corrosion Using Potentiometric Mg2+ Ion-selective Microelectrode. METSOC. Montreal, Canada
- (2013). Monitoring Magnesium Cation Release Dynamics during Magnesium Alloy Corrosion Using a Potentiometric Mg2+ Ion-selective Microelectrode. Surface Canada. London, Canada
- (2012). SECM study of Mg alloys galvanicaly coupled to steel and aluminum alloys to develop anti-corrosion mechanism for their industrial applications. NACE Northern Area Eastern Conference. Toronto, Canada