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Olivier Lesur

Professeur, Faculté de médecine et des sciences de la santé
FMSS Département de médecine

Présentation

Sujet de recherche

Appareil respiratoire, Maladies cardiovasculaires, Maladies inflammatoires du système respiratoire, Signalisation cellulaire, Système cardiovasculaire

Disciplines de recherche

Biologie cellulaire, Biologie moléculaire, Pneumologie

Mots-clés

Apeline, Défaillances organiques, Épithélium, Microimagerie, Perméabilité, Réparation/modelage, SDRA, Sepsis, Vasopressine, Ventilation mécanique

Intérêts de recherche

Le sepsis est l'archétype de la pathologie des soins intensifs capable de générer SDRA et autres défaillances multi-viscérales (cardiocirculatoires, rénales). Oedème et inflammation en sont les signes pathognomoniques. Les molécules et cellules impliquées dans ces processus sont étudiées, incluant les cytokines et neuropeptides. L'imagerie cellulaire et moléculaire in vivo est développée.

Centre de recherche

Centre de recherche du CHUS

Recherche clinique

Oui

Langues parlées et écrites

Anglais, Français

Diplômes

(2011). (Post-doctorat, Soins intensifs médicaux, CRMCC). Université de Sherbrooke.

(1996). (Post-doctorat, Pneumologie, CSPQ). Université de Sherbrooke.

(1992). (Doctorat, Biologie et biochimie cellulaire). Université de Nancy 1.

(1990). (Maîtrise avec mémoire, Biologie cellulaire - Maîtrise). Université de Sherbrooke.

(1990). (Post-doctorat, Pneumologie).

(1988). (Baccalauréat, Docteur en médecine - M.D.).

Titres de compétence

(1996) Permis de pratique restrictif (Pneumologie, S.I.). Collège des médecins du Québec.

Permis de pratique régulier (Pneumologie, S.I.). Collège des médecins du Québec.

Permis prise en charge Unité de S.I. (forfait).

Prix et distinctions

  • 40e Congrès international/Meilleure communication. (Distinction).
  • Conférencier GE Plante du Département de Médecine. (Distinction).
  • Meilleure communication affichée, 6e Journée Scientifique - RBIQ. (Distinction).
  • Prix Jean-De-Margerie - Meilleure publication 2007. (Distinction).

Publications

Articles de revue

  • Murza, Alexandre; Sainsily, Xavier; Coquerel, David; Côté, Jérôme; Marx, Patricia; Besserer-Offroy, Élie; Longpré, Jean-Michel; Lainé, Jean; Reversade, Bruno; Salvail, Dany; Leduc, Richard; Dumaine, Robert; Auger-Messier, Mannix; Lesur, Olivier; Sarret, Philippe; Marsault, Eric. (2015). Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions". Journal of Medicinal Chemistry (Révisions requises).
  • D. Coquerel, F. Chagnon, A. Murza, M. Auger-Messier, P. Sarret, E. Marsault, D. Salvail, O. Lesur. (2015). Effects of Apelin-13 analogs with C-terminal modification on healthy and septic heart. Canadian Journal of Cardiology 31 2015 (Article publié).
  • F Chagnon, A Bourgouin, R Lebel, MA Bonin, E Marsault, M Lepage, O Lesur. (2015). Smart Imaging of acute lung injury: exploration of myeloperoxidase (MPO) activity using in vivo endoscopic confocal fluorescence microscopy (ECFM). American Journal of Physiology. Lung cellular and molecular physiology 309 (6), L543-51. (Article publié).
  • A Bourgouin, MA Bonin, R Lebel, E Marsault, M Lepage, O Lesur. (2015). Synthesis and in vitro characterization of a fluorescent probe for myeloperoxidase activity detection. Chemistry & Biology (Article soumis).
  • J Lamoureux, T Fulop, O Lesur. (2015). Multiple dysfunctions and modified inflammatory marker's expression of neutrophils in severe sepsis and refractory septic shock patients; impact of corticosteroids (ex vivo and in vivo). Journal of Leukocyte Biology (Article soumis).
  • Murza A, Besserer-Offroy E, Côté J, Bérubé P, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Sarret P, Marsault E. (2015). C-terminal Modifications of apelin-13 significantly change ligand binding, receptor signaling and hypotensive action. Journal of medicinal chemistry 58 (5), 2431-40. (Article publié).
  • I Marois, A Cloutier, E Garneau, O Lesur, M Richter. (2015). The administration of oseltamivir results in reduced effector and memory CD8+ T cell responses to influenza and affects protective immunity. FASEB Journal: Official publication of the Federation af American societies of Experimental Biology 29 (3), 973-87. (Article publié).
  • Emmeline Ruka MD, Olivier Lesur MD, PhD, Pierre Voisine MD. (2015). Stroke and Transient Ischemic Attack in Patients Requiring Cardiac Surgery under Cardiopulmonary Bypass and who have Concomitant Carotid Disease. . (Article soumis).
  • McGovern Murphy F, Raymond M, Menard PA, Bejar-Ardiles KR, Carignan A, Lesur O. (2014). Ventilator associated pneumonia and endotracheal tube repositioning: An underrated risk factor. American Journal of Infectiology control 42 (12), 1328-30. (Article publié).
  • Gustot T, Felleiter P, Pickkers P, Sakr Y, Rello J, Velissaris D, Pierrakos C, Taccone FS, Sevcik P, Moreno C, Vincent JL; EPIC II Group of Investigators. (2014). Impact of infection on the prognosis of critically ill cirrhotic patients: results from a large worldwide study. Liver International: Official journal of the International Association for the study of the liver 34 (10), 1496-503. (Article publié).
  • F Chagnon, D Salvail, E Marsault, S Moore, D Coquerel, O Lesur. (2014). Apelin over dobutamine is cardioprotective and life-saving in a murine model of endotoxin-induced myocardial dysfunction. . (Article soumis).
  • McGovern-Murphy F, Raymond M, Ménard PA, Bejar-Ardiles KR, Carignan A, Lesur O. (2014). Ventilator Associated Pneumonia (VAP) and EndoTracheal tube (ETT) Repositioning: An Underrated Risk Factor. American Journal of Infection Control (Article publié).
  • De Waele J, Lipman J, Sakr Y, Marshall JC, Canhems P, Barrera Groba C, Leone M, Vincent JL; EPIC II Investigators. (2014). Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome. BMC Infectious Diseases 14 (420), 10.1186. (Article publié).
  • Williamson DR , Lesur O , Tétrault JP , Pilon D. (2014). Drug-induced thrombocytopenia in the critically ill: a case-control study. The Annals of pharmacotherapy 48 (6), 697-704. (Article publié).
  • Crowther M , Cook D , Guyatt G , Zytaruk N , McDonald E , Williamson D , Albert M , Dodek P , Finfer S , Vallance S , Heels-Ansdell D , McIntyre L , Mehta S , Lamontagne F , Muscedere J , Jacka M , Le. (2014). Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial. Journal of critical care 29 (3), 470.e7-15. (Article publié).
  • Lamontagne F , McIntyre L , Dodek P , Heels-Ansdell D , Meade M , Pemberton J , Skrobik Y , Seppelt I , Vlahakis NE , Muscedere J , Reece G , Ostermann M , Padayachee S , Alhashemi J , Walsh M , Lewis. (2014). Nonleg venous thrombosis in critically ill adults: a nested prospective cohort study. JAMA internal medicine 174 (5), 689-96. (Article publié).
  • Annane D , Siami S , Jaber S , Martin C , Elatrous S , Declère AD , Preiser JC , Outin H , Troché G , Charpentier C , Trouillet JL , Kimmoun A , Forceville X , Darmon M , Lesur O , Reignier J , Régnie. (2013). Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: the CRISTAL randomized trial. JAMA : the journal of the American Medical Association 310 (17), 1809-17. (Article publié).
  • Williamson DR, Albert M, Heels-Ansdell D, Arnold DM, Lauzier F, Zarychanski R, Crowther M, Warkentin TE, Dodek P, Cade J, Lesur O, Lim W, Fowler R, Lamontagne F, Langevin S, Freitag A. (2013). Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes. Chest 144 (4), 1207-15. (Article publié).
  • Warkentin TE, Sheppard JA, Heels-Ansdell D, Marshall JC, McIntyre L, Rocha MG, Mehta S, Davies AR, Bersten AD, Crozier TM, Ernest D, Vlahakis NE, Hall RI, Wood GG, Poirier G, Crowther MA, Cook DJ; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group. (2013). Heparin-induced thrombocytopenia in medical surgical critical illness. Chest. 144 (3), 848-58. (Article publié).
  • Beaulieu-Boire G , Bourque S , Chagnon F , Chouinard L , Gallo-Payet N , Lesur O. (2013). Music and biological stress dampening in mechanically-ventilated patients at the intensive care unit ward-a prospective interventional randomized crossover trial. Journal of critical care 28 (4), 442-50. (Article publié).
  • Williamson DR , Lesur O , Tétrault JP , Nault V , Pilon D. (2013). Thrombocytopenia in the critically ill: prevalence, incidence, risk factors, and clinical outcomes. Canadian journal of anaesthesia = Journal canadien d'anesthésie 60 (7), 641-51. (Article publié).
  • Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO; OSCILLATE Trial Investigators; Canadian Critical Care Trials Group. (2013). High-frequency oscillation in early acute respiratory distress syndrome. New England journal of medicine 368 (9), 795-805. (Article publié).
  • Smith OM, McDonald E, Zytaruk N, Foster D, Matte A, Clarke F, Meade L, O'Callaghan N, Vallance S, Galt P, Rajbhandari D, Rocha M, Mehta S, Ferguson ND, Hall R, Fowler R, Burns K, Qushmaq I, Ostermann M, Heels-Ansdell D, Cook D. (2013). Rates and determinants of informed consent: a case study of an international thromboprophylaxis trial. Journal of critical care 28 (1), 28-39. (Article publié).
  • Cook D, McDonald E, Simth O, Zytaruk N, Heels-Ansdell D, Watpool I, McArdle T, Matte A, Clarke F, Vallance S, Finfer S, Galt P, Crozier T, Fowler R, Arabi Y, Woolfe C, Orford N, Hall R, Adhikari NK, Ferland MC, Marshall J, Meade M; PROTECT Research Coordinators; PROTECT Investigators; Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group. (2013). Co-enrollment of critically ill patients into multiple studies: patterns, predictors and consequences. Crit Care 17 (1), R1.doi:10.1186. (Article publié).
  • Fan E , Checkley W , Stewart TE , Muscedere J , Lesur O , Granton JT , Freitag AP , Jacka M , Ferguson ND , Meade MO. (2012). Complications from recruitment maneuvers in patients with acute lung injury: secondary analysis from the lung open ventilation study. Respiratory care 57 (11), 1842-9. (Article publié).
  • Solana R , Tarazona R , Gayoso I , Lesur O , Dupuis G , Fulop T. (2012). Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans. Seminars in immunology 24 (5), 331-41. (Article publié).
  • Hogue B , Chagnon F , Lesur O. (2012). Resuscitation fluids and endotoxin-induced myocardial dysfunction: is selection a load-independent differential issue?. Shock (Augusta, Ga.) 38 (3), 307-13. (Article publié).
  • Ranieri VM , Thompson BT , Barie PS , Dhainaut JF , Douglas IS , Finfer S , Gårdlund B , Marshall JC , Rhodes A , Artigas A , Payen D , Tenhunen J , Al-Khalidi HR , Thompson V , Janes J , Macias WL. (2012). Drotrecogin alfa (activated) in adults with septic shock. The New England journal of medicine 366 (22), 2055-64. (Article publié).
  • Lesur O , Hermans C. (2012). The complement system as another target for inhibition in septic patients: should we implement this treatment or wait for the evidence?. Critical care medicine 40 (3), 988-90. (Article publié).
  • Lauzier F , Lesur O. (2011). Arginine-vasopressin and corticosteroids in septic shock: engaged but not yet married!. Intensive care medicine 37 (9), 1406-8. (Article publié).
  • Merk M , Zierow S , Leng L , Das R , Du X , Schulte W , Fan J , Lue H , Chen Y , Xiong H , Chagnon F , Bernhagen J , Lolis E , Mor G , Lesur O , Bucala R. (2011). The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF). Proceedings of the National Academy of Sciences of the United States of America 108 (34), (Article publié).
  • F Chagnon. (2010). Endotoxin-induced acute hypothalamo-pituitary-adrenal axis dysfunction: impact of arginine-vasopressin (AVP) and apelin (APL) exogenous administrations. Am J Physiol Endoc Metab (Article publié).
  • Lamontagne F , Briel M , Duffett M , Fox-Robichaud A , Cook DJ , Guyatt G , Lesur O , Meade MO. (2010). Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis. Critical care medicine 38 (12), 2401-8. (Article publié).
  • Bossé D , Walti H , Robert R , Lebon J , Lesur O , Praud JP , Micheau P. (2010). Experimental validation of cardiac index measurement using transpulmonary thermodilution technique in neonatal total liquid ventilation. American Society for Artificial Internal Organs Journal : 1992 56 (6), 557-62. (Article publié).
  • Chagnon F , Fournier C , Charette PG , Moleski L , Payet MD , Dobbs LG , Lesur O. (2010). In vivo intravital endoscopic confocal fluorescence microscopy of normal and acutely injured rat lungs. Laboratory investigation; a journal of technical methods and pathology 90 (6), 824-34. (Article publié).
  • Lesur O , Remillard MA , St-Pierre C , Falardeau S. (2010). Prophylactic positive end-expiratory pressure and postintubation hemodynamics: an interventional, randomized study. Canadian respiratory journal : journal of the Canadian Thoracic Society 17 (3), e45-50. (Article publié).
  • Chamberland C , Barajas-Martinez H , Haufe V , Fecteau MH , Delabre JF , Burashnikov A , Antzelevitch C , Lesur O , Chraibi A , Sarret P , Dumaine R. (2010). Modulation of canine cardiac sodium current by Apelin. Journal of molecular and cellular cardiology 48 (4), 694-701. (Article publié).
  • Fortin CF , McDonald PP , Fülöp T , Lesur O. (2010). Sepsis, leukocytes, and nitric oxide (NO): an intricate affair. Shock (Augusta, Ga.) 33 (4), 344-52. (Article publié).
  • B. Daneaulta, J.-F. Delabreb, R. Dumaine, B. Hoguec, F. Chagnonc, O. Lesur. (2010). Apeline, a new promising molecule for the treatment of acute heart failure?. Réanimation 19 (2), 171-178. (Article publié).
  • Leclair MA , Allard C , Lesur O , P�pin J. (2010). Clostridium difficile infection in the intensive care unit. Journal of intensive care medicine 25 (1), 23-30. (Article publié).
  • Lesur O , Roussy JF , Chagnon F , Gallo-Payet N , Dumaine R , Sarret P , Chraibi A , Chouinard L , Hogue B. (2010). Proven infection-related sepsis induces a differential stress response early after ICU admission. Critical care (London, England) 14 (4), R131. (Article publié).
  • Maxime V , Lesur O , Annane D. (2009). Adrenal insufficiency in septic shock. Clinics in chest medicine 30 (1), 17-27, vii. (Article publié).
  • Lesur O , Rousseau E. (2009). "Pas de DEux" for phosphodiesterase-2 in acute lung injury. Critical care medicine 37 (2), 769-70. (Article publié).
  • Lamontagne F , Meade M , Ondiveeran HK , Lesur O , Fox-Robichaud AE , Robichaud AE. (2008). Nitric oxide donors in sepsis: a systematic review of clinical and in vivo preclinical data. Shock (Augusta, Ga.) 30 (6), 653-9. (Article publié).
  • Chagnon F , Bentourkia M , Lecomte R , Lessard M , Lesur O. (2006). Endotoxin-induced heart dysfunction in rats: assessment of myocardial perfusion and permeability and the role of fluid resuscitation. Critical care medicine 34 (1), 127-33. (Article publié).
  • Chagnon F , Metz CN , Bucala R , Lesur O. (2005). Endotoxin-induced myocardial dysfunction: effects of macrophage migration inhibitory factor neutralization. Circulation research 96 (10), 1095-102. (Article publié).
  • Gibot S , Lévy B , Nevière R , Cariou A , Lesur O. (2004). [Myocardial dysfunction and septic shock]. Médecine sciences : M/S 20 (12), 1115-8. (Article publié).

Chapitres de livre

  • L. Guay, Y. Poulin, L. Valiquette, G. Schmutz, O. Lesur. (2010). Les colites infectieuses aigues. Chapitre, Réanimation Hépatosplanchnique (2009, Pages 247-265). Elsevier SAS. (Article publié).
  • O. Lesur, P.G. Charette, Ph Jouvet, F. Cheriet, F. Chagnon. (2010). Towards in vivo microimaging of lung inflammation and repair: current issues and future directions. Microscopy : Science, Technology, Applications and Education (1, 633-640). A.Méndez-Vilas and J.Diaz (Eds). (Article publié).
  • F. Lamontagne, F. Bénard, O. Lesur. (2003). Positron Emission Tomography: Anticipated usefulness in Clinical and Experimental Critical Care Settings. Year Book of Intensive Care and Emergency Medicine (2003, 737-746). Jean-Louis Vincent. (Article publié).
  • F. Lauzier, N. Gallo-Payet, O. Lesur. Vasopressin and Hypothalamic-Pituitary-Adrenal axis relationships: Old knowledge … but potential new applications in Critical Care Setting. Year Book of Intensive Care and Emergency Medicine (2003, 901-911). Jean-Louis Vincent. (Article publié).

Articles de conférence

  • E. Ruka, O. Lesur, M. Buruian, É. Voisine, F. Dagenais, V. Chauvette, P. Voisine. (2015). Carotid stenosis is an independant preditor of post-operative stroke in on-pump cardiac surgery. Canadian Journal of Cardiology, (Article publié).
  • Jessica Perez, Norma Ubarra, Frederic Chagnon, Olivier Lesur, Issam El Naqa. (2015). Quantitative image analysis of fluorescence endomicroscopy video sequences for mesenchymal stem cell tracking in regenerative lung treatment. World Congress on Meidcal Physics & Biomedical Engineering. (Article publié).
  • Alexandre Murza, Élie Besserer-Offroy, Jérôme Coté, Patrick Bérubé, Jean-Michel Longpré, Robert Dumaine, Olivier Lesur, Mannix Auger-Messier, Philippe Sarret, Éric Marsault. (2015). Conception, synthèse et exploration de la relation structure-fonction de nouveaux analogues macrocycliques de l'apéline-13. 4e Journée Scientifique DOCC. (Article publié).
  • Olivier Lesur, Frédéric Chagnon, Alexandra Bourgouin, Réjean Lebel, Marc-André Bonin, Eric Marsault, Martin Lepage. (2015). Smart imaging of acute lung injury: exploration of myeloperoxidase (MPO) activity using in vivo endoscopic confocal fluorescence microscopy (ECFM). 7th Internation Conference of Cellvizio Users. (Article publié).
  • David Coquerel, Frédéric Chagnon, Alexandre Murza, Mannix Auger-Messier, Philippe Sarret, Éric Marsault, Dany Salvail, Olivier Lesur. (2015). Effet de l'apéline-13 et des analogues modifiés en C-terminal sur la fonction cardiaque en condition physiologique et d'agression septique. 4e Journée scientifique DOCC. (Article publié).
  • David Coquerel, Frédéric Chagnon, Alexandre Murza, Mannix Auger-Messier, Philippe Sarret, Éric Marsault, Olivier Lesur. (2015). Effet de l'apéline-13 et de ses analogues modifiés en C-terminal sur la fonction cardiaque en condition physiologique et d'agression septique. 4e Journée Scientifique DOCC. (Article publié).
  • O Lesur, F Chagnon, A Murza, P Sarret, E Marsault, D Salvail. (2014). Apelin is cardioprotective and life-saving over dobutamine in a murine model of endotoxin-induced myocardial dysfunction. Intensive Care Medicine Experimental 2014, (Article publié).
  • Lesur O, Perez J, Ybarra N, Maria O, Chagnon F, El Naqa I,. (2014). In Vivo Fluorescence Imaging and Endomicroscopy for Tracking of Mesenchymal Stem Cells in Post-Radiotherapy Lung Injury. ISSCR 12th Annual Meeting. (Article publié).
  • Lesur O, Chagnon F, Murza A, Sarret P, Marsault E, Salvail D. (2014). Apelin is cardioprotective and life-saving over Dobutamine in a murine model of endotoxin-induced myocardial dysfunction. European Society of Intensive Care Medicine. (Article publié).
  • Perez J, Vallières M, Ybarra N, Maria O, Chagnon F, Lesur O, El Naqa I. (2014). Fluorescence Endomicroscopy as a Tool to Assess Radiation-Induced Lung Damage, Protection and Regeneration. American Society for Radiation Oncology. (Article publié).
  • Perez J, Ybarra N, Maria O, Chagnon F, Lesur O, El Naqa I. (2014). In Vivo Fluorescence Imaging and Endomicroscopy for Tracking of Mesenchymal Stem Cells in Post-Radiotherapy Lung Injury. International Society For Stem Cell Research. (Article publié).
  • Chagnon F, Bourgouin A, Bonin MA, Lebel R, Marsault E, Lesur O, Lepage M. (2014). Molecular Imaging of Acute Lung Injury : Detection of Myeloperoxidase (MPO) Activity Using in vivo Confocal Fluorescence Endomicroscopy. World Molecular Imaging Congress. (Article publié).
  • Perez J, Vallières M, Ybarra N, Maria O, Chagnon F, Lesur O, El Naqa I. (2014). Fluorescence Endomicroscopy as a tool to Assess Radiation-Induced Lung Damage, Protection and Regeneration. American Society for Radiation Oncology (ASTRO). (Article publié).
  • Perez J, Ybarra N, Maria O, Chagnon F, Lesur O, El Naqa I. (2014). In Vivo Fluorescence Imaging and Endomicroscopy for Tracking of Mesenchymal Stem Cells in Post-Radiotherapy Lung Injury. International Society For Stem Cell Research. (Article publié).
  • Perez J, Vallières M, Ybarra N, Maria O, Chagnon F, Lesur O, El Naqa I. (2014). Texture Analysis for Quantitative Evaluation of Fluorescence Endomicroscopy Images in Radiation-Induced Lung Damage. The Canadian Organization of Medical Physicists. (Article publié).
  • *Lamoureux J, Fülöp T, Lesur O. (2014). Neutrophil's behavior in severe and refractory human sepsis : impact of corticosteroids (in vivo and in vitro). International Symposium Neutrophil 2014. (Article publié).
  • Lesur O, Perez J, Vallières M, Ybarra N, Maria O, Chagnon F, El Naqa I,. (2014). Fluorescence Endomicroscopy as a Tool to Assess Radiation-Induced Lung Damage, Protection and Regeneration. Astros's 56th Annual Meeting Targeting Cancer : Technology & Biology. (Article publié).
  • Zaglam N, chriet F, Lesur O, Jouvet P. (2013). Multimodal registration of pulmonary images for the continuous monitoring of regional ventilation. WCPCCICS. (Article publié).
  • Lesur O et al. (2013). Repositioning The Endotracheal Tube : An Underrated Risk Factor For Ventilator Associated Pneumonia. 11th Congress of the World Federation of Societies of Intensive and Critical Care Medicine. (Article publié).
  • F McGovern et al. (2012). Repositioning the endotracheal tube: an underrated risk factor for ventilator associated pneumonia. Am J Resp Crit Care Med, (Article publié).
  • Eric Marsault, Alexandre Murza, Élie Besserer-Offroy, Jérôme Côté, Jean-Michel Longpré, David Coquerel, Robert Dumaine, Mannix Auger-Messier, Olivier Lesur, Michel Bouvier, Pierre Lavigne, Richard Leduc, Philippe Sarret. Deciphering the structure-function of apelin with unnatural amino acids and macrocycles. Journée Scientifique du RQRM. (Article accepté).

Autres contributions

Présentations

  • (2015). Smart imaging of acute lung injury: exploration of myeloperoxidase (MPO) activity using in vivo endoscopic confocal fluorescence microscopy (ECFM). ICCU - 7th International Conference of Cellvizio Users. Lisbon
  • (2014). In vivo endoscopic confocal fluorescence microscopy (ECFM):“vers une biopsie virtuelle” Personnaliser le diagnostic, le suivi, et le traitement des atteintes pulmonaires sévères. Institut de recherches cliniques de Montréal. Montréal
  • (2013). Improving the evaluation of cardiac function in rats at 7T by using non-local means filtering. Journée française de Radiologie 2013. Paris
  • (2012). In vivo endoscopic confocal fluorescence microscopy (ECFM) of the lung: Abyssal travel... for a virtual biopsy. Noon seminar Series 2012-2013 - Medical physics unit. Montréal
  • (2012). Bronchoscopic Confocal Imaging in Human Lung. ATS. San Francisco
  • (2012). La microscopie par bronchoscopie. 14e Symposium québécois des soins intensifs. Sherbrooke
  • (2012). Vers une microimagerie pulmonaire in vivo, au chevet, aux soins intensifs. Apportez votre pathologiste dans votre poche!14e Symposium québécois de SI, Sherbrooke, février 2012. 14e Symposium québécois de Soins intensifs. Sherbrooke
  • (2012). MONITOREP ou MONitorage Intra Thoracique Optique de la Réparation Pulmonaire in vivo. 4e Journée scientifique Réseau de bio-imagerie du Québec. Montréal
  • (2011). Implementing modern microscopy for imaging living cells and intact animals. 2011 ATS meeting. Denver
  • (2010). In vivo endoscopic confocal fluorescence microscopy of the lung: the cutting edge of abyssal travel... without cutting out?. Watching the Lung work. International Symposium University of Giessen and Marburg Lung Center. Allemagne
  • (2010). Modern lung imaging special topic session. ATS. Denver
  • (2009). Le monitorep. Symposium France-Québec 2009. Québec