Martin Bisaillon

Prix et distinctions

• (2016) Chercheur-boursier Sénior. Fonds de recherche du Québec - Santé (FRQS). (Prix).
• (2012) Chercheur-boursier Junior II. Fonds de recherche du Québec - Santé (FRQS). (Prix).
• (2008) New Investigator Award. Instituts de recherche en santé du Canada. (Prix).
• (2006) Chercheur-boursier Junior 1. Fonds de recherche du Québec - Santé (FRQS). (Prix).
• Excellence in Teaching Award. Université de Sherbrooke. (Prix).
• Marcel-Bastin Award for outstanding teaching. Université de Sherbrooke. (Prix).
• Marcel-Bastin Award for outstanding teaching. Université de Sherbrooke. (Prix).
• Marcel-Bastin Award for outstanding teaching. Université de Sherbrooke. (Prix).

Financement

• Subvention. (Obtenu). Cocandidat. Contact killing of COVID-19 by copper-based nanoparticles.. Conseil de Recherches en Sciences Naturelles et Génie du Canada (CRSNG). Alliance Grant – COVID-19. 50 000 $. (2020-2021)
• Subvention. (Obtenu). Candidat principal. Molecular basis of protein-ligand interactions.. Conseil de Recherches en Sciences Naturelles et Génie du Canada (CRSNG). Discovery Grants Program. 145 000 $. (2016-2021)
• Subvention. (Obtenu). Cocandidat. Mechanisms of antiviral drug resistance for Herpesviruses.. (2015-2020)
• Subvention. (Obtenu). Cocandidat. Nouveaux biomarqueurs pour la détection précoce du cancer oropharyngé.. Département de chirurgie - FMSS. Research funds. 32 000 $. (2017-2018)
• Subvention. (Obtenu). Cochercheur. Développement et validation d’essais moléculaires d’expression génique permettant une meilleure stratification du risque associé aux oligodendrogliomes IDH-mutés 1p/19q-codélétés et aux gliomes IDH-wt.. Merck Sharpe & Dohme. Research funds. 67 000 $. (2017-2018)
• Subvention. (Obtenu). Cochercheur. Nouveaux biomarqueurs urinaires pour la détection de récidive tumorale : les événements d’épissage alternatif comme nouvel outil diagnostic chez les patients atteints du cancer de la vessie. Merck Sharpe & Dohme. Research funds. 67 000 $. (2017-2018)
• Subvention. (Obtenu). Cocandidat. Development of serodiagnostic biomarkers for Candidemia.. Instituts de Recherche en Santé du Canada (IRSC). Project Grant. 100 000 $. (2016-2017)
• Subvention. (Obtenu). Cocandidat. Études structurales et fonctionnelles d'une nouvelle classe de protéines transportant l'hème.. (2015-2017)
• Bourse de recherche. (Obtenu). Chercheur principal. Caractérisation des déterminants moléculaires impliqués dans la maturation des ARN viraux.. (2012-2016)
• Subvention. (Obtenu). Candidat principal. Modifications des événements d'épissage alternatif dans les cancers induits par les virus: un nouveau paradigme pour la recherche translationnelle et la médecine personnalisée.. (2015-2016)
• Subvention. (Obtenu). Candidat principal. Molecular basis of protein-ligand interactions.. (2015-2016)
• Subvention. Molecular basis of protein-ligand interactions.. (2015-2016)
• Subvention. (Obtenu). Cochercheur. Nouveau biomarqueur pour contrer les fungémies. Centre de recherche clinique du CHUS. Programme PAFI. 25 000 $. (2015-2016)
• Subvention. (Obtenu). Candidat principal. Modifications de l'épissage alternatif de gènes impliqués dans le cancer lors d'infections virales.. (2014-2015)
• Subvention. (Obtenu). Cochercheur. Centre de biologie de l'ARN. (2012-2015)
• Subvention. (Obtenu). Cocandidat. Innovative and flexible tools for protein purification and molecule binding studies.. (2014-2015)
• Subvention. (Obtenu). Chercheur principal. Molecular basis of protein-ligand interactions. (2010-2015)
• Subvention. (Obtenu). Chercheur principal. Biological implications of RNA decapping during vaccinia virus infection.. (2012-2015)
• Bourse de recherche. (Terminé). Chercheur principal. Caractérisation des déterminants moléculaires impliqués dans la synthèse et la maturation des ARN viraux.. (2008-2012)
• Subvention. (Terminé). Chercheur principal. Biological implications of RNA decapping during vaccinia virus infection.. (2011-2012)
• Subvention. (Terminé). Cochercheur. Centre de biologie de l'ARN. (2009-2012)
• Subvention. (Terminé). Chercheur principal. Characterization of the molecular determinants involved in the synthesis and maturation of viral RNAs.. (2006-2011)
• Subvention. (Terminé). Cochercheur. Platform for the study of RNA structure, function, and evolution. (2005-2010)
• Subvention. (Terminé). Chercheur principal. Development of a SOFA-ribozyme-based strategy to control the propagation of the influenza virus.. (2009-2010)
• Subvention. (Terminé). Chercheur principal. Structural and mechanistic studies of proteins involved in the replication of the West Nile virus.. (2004-2009)
• Subvention. (Terminé). Cochercheur. Acquisition of an imaging system for quantification of DNA, RNA, and proteins.. (2008-2009)
• Subvention. (Terminé). Chercheur principal. Development of a SOFA-ribozyme-based strategy to control the propagation of the influenza virus. (2008-2009)
• Bourse de recherche. (Terminé). Chercheur principal. Identification and characterization of molecular determinants involved in the RNA capping chemistry of viral proteins.. (2003-2008)
• Subvention. (Terminé). Cochercheur. Acquisition of a scintillation counter. (2007-2008)
• Subvention. (Terminé). Cochercheur. A metal-free water purification system. (2006-2007)
• Bourse de recherche. Élucidation du mécanisme moléculaire des protéines impliquées dans la synthèse de la structure coiffe des ARN messagers.. (2002-2006)
• Subvention. (Terminé). Chercheur principal. A centrifuge for the analysis and characterization of proteins.. (2005-2006)
• (Terminé). Chercheur principal. Identification and characterization of the molecular determinants involved in the RNA capping chemistry of viral proteins.. (2003-2006)
• (Terminé). Chercheur principal. Élucidation du mécanisme moléculaire des protéines impliquées dans la synthèse de la structure coiffe des ARN messagers.. (2002-2005)
• (Terminé). Chercheur principal. Combined experimental approaches for the study of protein-ligand interactions.. (2004-2004)
• (Terminé). Chercheur principal. Élucidation du mécanisme moléculaire des protéines impliquées dans la synthèse de la structure coiffe des ARN messagers.. (2002-2003)
• Subvention. (Terminé). Chercheur principal. Caractérisation des déterminants moléculaires impliqués dans la synthèse et la maturation des ARN viraux.. (2002-2003)
• Bourse de recherche. (1999-2002)
• Bourse de recherche. (1999-2001)
• Bourse de recherche. (1998-1999)
• Bourse de recherche. (1997)
• Bourse de recherche. (1997)
• Bourse de recherche. (1992-1993)
• Bourse de recherche. (1991-1992)

Publications

Articles de revue

• Nguyen HD, *Allaire A, Diamandis P, Bisaillon M, Scott MS, Richer M. (2020). A machine learning analysis of a "normal-like" IDH-WT diffuse glioma transcriptomic subgroup associated with prolonged survival reveals novel immune and neurotransmitter-related actionable targets. BMC Med 18 (1), 280. (Article publié).
• *Brodeur CM, Thibault P, Durand M, Perreault JP, Bisaillon M. (2019). Dissecting the expression landscape of cytochromes P450 in hepatocellular carcinoma: towards novel molecular biomarkers. Genes Cancer 10 97-108. (Article publié).
• *Jodoin R, Carrier J, Rivard N, Bisaillon M, Perreault JP. (2019). G-quadruplex located in the 5’UTR of the BAG-1 mRNA affects both its cap-dependent and cap-independent translation through global secondary structure maintenance. Nucleic Acids Res 47 10247-10266. (Article publié).
• Lanoie D, *Boudreault S, Bisaillon M, Lemay G. (2019). How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?. Pathogens 8 E83. (Article publié).
• *Boudreault S, *Armero VES, Scott MS, Perreault JP, Bisaillon M. (2019). The Epstein-Barr virus EBNA1 protein modulates the alternative splicing of cellular genes. Virol J 16 29. (Article publié).
• *Boudreault S, Roy P, Lemay G, Bisaillon M. (2019). Viral modulation of cellular RNA alternative splicing: A new key player in virus-host interactions?. Wiley Interdiscip Rev RNA 10 e1543. (Article publié).
• *Picard-Jean F, *Brand C, Tremblay-Létourneau M, *Allaire A, Beaudoin MC, *Boudreault S, *Duval C, *Rainville-Sirois J, Robert F, Pelletier J, Geiss BJ, Bisaillon M. (2018). 2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO. PLoS One 13 (3), e0193804. (Article publié).
• *Rouleau SG, Garant JM, Bolduc F, Bisaillon M, Perreault JP. (2018). G-Quadruplexes influence pri-microRNA processing. RNA Biol. 15 (2), 198-206. (Article publié).
• *Rouleau SG, Glouzon JS, Brumwell A, Bisaillon M, Perreault JP. (2017). 3' UTR G-Quadruplexes regulate miRNA binding. RNA May 4 1172-1179. (Article sous presse).
• *Brand C, Bisaillon M, Geiss BJ. (2017). Organization of the Flavivirus RNA replicase complex. Wiley Interdiscip Rev RNA. 8 (6), e1437. (Article publié).
• *Armero VES, *Tremblay MP, *Allaire A, *Boudreault S, *Martenon-Brodeur C, *Duval C, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Bisaillon M. (2017). Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas. PLoS One 12 (5), e0176880. (Article publié).
• *Boudreault S, *Martenon-Brodeur C, Caron M, Garant JM, *Tremblay MP, *Armero VE, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Lemay G, Bisaillon M. (2016). Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions. PLoS One 11 e0161914. (Article publié).
• *Tremblay MP, *Armero VE, *Allaire A, *Boudreault S, *Martenon-Brodeur C, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Bisaillon M. (2016). Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma. BMC Genomics 17 683. (Article publié).
• *Allaire A, *Picard-Jean F, Bisaillon M. (2015). Immunofluorescence to monitor the cellular uptake of human lactoferrin and its associated antiviral activity against the Hepatitis C Virus. J Vis Exp 104 doi: 10.3791/53053. (Article publié).
• Mourer T, Jacques JF, Brault A, Bisaillon M, Labbe S. (2015). Shu1 is a cell-surface protein involved in iron acquisition from heme in Schizosaccharomyces pombe. J Biol Chem 290 (16), 10176-10190. (Article publié).
• *Rouleau SG, Beaudoin JD, Bisaillon M, Perreault JP. (2015). Small antisense oligonucleotides against G-quadruplexes: specific mRNA translational switches. Nucleic Acids Res 43 (1), 595-606. (Article publié).
• *Picard-Jean F, *Bouchard S, *Larivée G, Bisaillon M. (2014). The intracellular inhibition of HCV replication represents a novel mechanism of action by the innate immune Lactoferrin protein. Antiviral Res. 111C 13-22. (Article publié).
• Wypijewska del Nogal A , Surleac MD , Kowalska J , Lukaszewicz M , Jemielity J , Bisaillon M , Darzynkiewicz E , Milac AL , Bojarska E. (2013). Analysis of decapping scavenger cap complex using modified cap analogs reveals molecular determinants for efficient cap binding. The FEBS journal 280 (24), 6508-27. (Article publié).
• Issur M , Bougie I , Despins S , Bisaillon M. (2013). Enzymatic synthesis of RNAs capped with nucleotide analogues reveals the molecular basis for substrate selectivity of RNA capping enzyme: impacts on RNA metabolism. PLoS one 8 (9), e75310. (Article publié).
• Picard-Jean F , Bougie I , Shuto S , Bisaillon M. (2013). The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme. PLoS one 8 (1), e54621. (Article publié).
• Anderson DE , Castan A , Bisaillon M , von Messling V. (2012). Elements in the canine distemper virus M 3' UTR contribute to control of replication efficiency and virulence. PLoS one 7 (2), e31561. (Article publié).
• Lemay G , Bisaillon M. (2012). Further characterization and determination of the single amino acid change in the tsI138 reovirus thermosensitive mutant. Canadian Journal of Microbiology 58 (5), 589-95. (Article publié).
• Rouleau SG , Jodoin R , Bisaillon M , Perreault JP. (2012). Programming a highly structured ribozyme into complex allostery using RNA oligonucleotides. ACS chemical biology 7 (11), 1802-6. (Article publié).
• Motard J , Rouxel R , Paun A , von Messling V , Bisaillon M , Perreault JP. (2011). A novel ribozyme-based prophylaxis inhibits influenza A virus replication and protects from severe disease. PLoS one 6 (11), e27327. (Article publié).
• Dubé A , Bolduc F , Bisaillon M , Perreault JP. (2011). Mapping studies of the Peach latent mosaic viroid reveal novel structural features. Molecular Plant Pathology 12 (7), 688-701. (Article publié).
• Issur M , Picard-Jean F , Bisaillon M. (2011). The RNA capping machinery as an anti-infective target. Wiley interdisciplinary reviews. RNA 2 (2), 184-92. (Article publié).
• Tremblay-Létourneau M , Despins S , Bougie I , Bisaillon M. (2011). Virtual high-throughput screening identifies mycophenolic acid as a novel RNA capping inhibitor. PLoS one 6 (9), e24806. (Article publié).
• Despins S , Issur M , Bougie I , Bisaillon M. (2010). Deciphering the molecular basis for nucleotide selection by the West Nile virus RNA helicase. Nucleic Acids Research 38 (16), 5493-506. (Article publié).
• Reymond C , Lévesque D , Bisaillon M , Perreault JP. (2010). Developing three-dimensional models of putative-folding intermediates of the HDV ribozyme. Structure (London, England : 1993) 18 (12), 1608-16. (Article publié).
• Soulière MF , Perreault JP , Bisaillon M. (2010). Insights into the molecular determinants involved in cap recognition by the vaccinia virus D10 decapping enzyme. Nucleic Acids Research 38 (21), 7599-610. (Article publié).
• Dubé A , Baumstark T , Bisaillon M , Perreault JP. (2010). The RNA strands of the plus and minus polarities of peach latent mosaic viroid fold into different structures. RNA (New York, N.Y.) 16 (3), 463-73. (Article publié).
• Soulière MF , Perreault JP , Bisaillon M. (2009). Characterization of the vaccinia virus D10 decapping enzyme provides evidence for a two-metal-ion mechanism. The Biochemical journal 420 (1), 27-35. (Article publié).
• Dubé A , Bisaillon M , Perreault JP. (2009). Identification of proteins from prunus persica that interact with peach latent mosaic viroid. Journal of virology 83 (23), 12057-67. (Article publié).
• Bougie I , Bisaillon M. (2009). Metal ion-binding studies highlight important differences between flaviviral RNA polymerases. Biochimica et biophysica acta 1794 (1), 50-60. (Article publié).
• Reymond C , Bisaillon M , Perreault JP. (2009). Monitoring of an RNA multistep folding pathway by isothermal titration calorimetry. Biophysical journal 96 (1), 132-40. (Article publié).
• Issur M , Despins S , Bougie I , Bisaillon M. (2009). Nucleotide analogs and molecular modeling studies reveal key interactions involved in substrate recognition by the yeast RNA triphosphatase. Nucleic acids research 37 (11), 3714-22. (Article publié).
• Issur M , Geiss BJ , Bougie I , Picard-Jean F , Despins S , Mayette J , Hobdey SE , Bisaillon M. (2009). The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure. RNA (New York, N.Y.) 15 (12), 2340-50. (Article publié).
• Soulière MF , Perreault JP , Bisaillon M. (2008). Kinetic and thermodynamic characterization of the RNA guanylyltransferase reaction. Biochemistry 47 (12), 3863-74. (Article publié).
• Soulière MF , Perreault JP , Bisaillon M. (2008). Magnesium-binding studies reveal fundamental differences between closely related RNA triphosphatases. Nucleic acids research 36 (2), 451-61. (Article publié).
• Picard-Jean F , Bougie I , Bisaillon M. (2007). Characterization of the DNA- and dNTP-binding activities of the human cytomegalovirus DNA polymerase catalytic subunit UL54. The Biochemical journal 407 (3), 331-41. (Article publié).
• Bougie I , Bisaillon M. (2007). Characterization of the RNA binding energetics of the Candida albicans poly(A) polymerase. Yeast (Chichester, England) 24 (5), (Article publié).
• Reymond C , Ouellet J , Bisaillon M , Perreault JP. (2007). Examination of the folding pathway of the antigenomic hepatitis delta virus ribozyme reveals key interactions of the L3 loop. RNA (New York, N.Y.) 13 (1), (Article publié).
• Fillebeen C , Muckenthaler M , Andriopoulos B , Bisaillon M , Mounir Z , Hentze MW , Koromilas AE , Pantopoulos K. (2007). Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells. Journal of hepatology 47 (1), (Article publié).
• Benzaghou I , Bougie I , Picard-Jean F , Bisaillon M. (2006). Energetics of RNA binding by the West Nile virus RNA triphosphatase. FEBS letters 580 (3), (Article publié).
• Bougie I , Bisaillon M. (2006). Inhibition of a metal-dependent viral RNA triphosphatase by decavanadate. The Biochemical journal 398 (3), (Article publié).
• Parent A , Bisaillon M. (2006). [Synergy between transcription and mRNA processing events]. Médecine sciences : M/S 22 (6-7), (Article publié).
• Fillebeen C , Rivas-Estilla AM , Bisaillon M , Ponka P , Muckenthaler M , Hentze MW , Koromilas AE , Pantopoulos K. (2005). Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus. The Journal of biological chemistry 280 (10), (Article publié).
• Yan Y , Svitkin Y , Lee JM , Bisaillon M , Pelletier J. (2005). Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap. RNA (New York, N.Y.) 11 (8), (Article publié).
• Benzaghou I , Bougie I , Bisaillon M. (2004). Effect of metal ion binding on the structural stability of the hepatitis C virus RNA polymerase. The Journal of biological chemistry 279 (48), (Article publié).
• Bougie I , Bisaillon M. (2004). The broad spectrum antiviral nucleoside ribavirin as a substrate for a viral RNA capping enzyme. The Journal of biological chemistry 279 (21), (Article publié).
• Bougie I , Parent A , Bisaillon M. (2004). Thermodynamics of ligand binding by the yeast mRNA-capping enzyme reveals different modes of binding. The Biochemical journal 384 (Pt 2), (Article publié).
• Bougie I , Charpentier S , Bisaillon M. (2003). Characterization of the metal ion binding properties of the hepatitis C virus RNA polymerase. The Journal of biological chemistry 278 (6), (Article publié).
• Bougie I , Bisaillon M. (2003). Initial binding of the broad spectrum antiviral nucleoside ribavirin to the hepatitis C virus RNA polymerase. The Journal of biological chemistry 278 (52), (Article publié).
• Bisaillon M , Bougie I. (2003). Investigating the role of metal ions in the catalytic mechanism of the yeast RNA triphosphatase. The Journal of biological chemistry 278 (36), (Article publié).
• Bisaillon M , Shuman S. (2001). Functional groups required for the stability of yeast RNA triphosphatase in vitro and in vivo. The Journal of biological chemistry 276 (32), (Article publié).
• Bisaillon M , Shuman S. (2001). Structure-function analysis of the active site tunnel of yeast RNA triphosphatase. The Journal of biological chemistry 276 (20), (Article publié).
• Bisaillon M , Sénéchal S , Bernier L , Lemay G. (1999). A glycosyl hydrolase activity of mammalian reovirus sigma1 protein can contribute to viral infection through a mucus layer. Journal of molecular biology 286 (3), (Article publié).
• Bisaillon M , Lemay G. (1999). Computational sequence analysis of mammalian reovirus proteins. Virus genes 18 (1), (Article publié).
• Bisaillon M , Bergeron J , Lemay G. (1997). Characterization of the nucleoside triphosphate phosphohydrolase and helicase activities of the reovirus lambda1 protein. The Journal of biological chemistry 272 (29), (Article publié).
• Bisaillon M , Lemay G. (1997). Characterization of the reovirus lambda1 protein RNA 5'-triphosphatase activity. The Journal of biological chemistry 272 (47), (Article publié).
• Bisaillon M , Lemay G. (1997). Molecular dissection of the reovirus lambda1 protein nucleic acids binding site. Virus research 51 (2), (Article publié).
• Bisaillon M , Lemay G. (1997). Viral and cellular enzymes involved in synthesis of mRNA cap structure. Virology 236 (1), (Article publié).

Chapitres de livre

• Picard-Jean F, Tremblay-Létourneau M, Serra E, Dimech C, Schulz H, Anselin M, Dutilly V, Bisaillon M. (2013). RNA 5'-end maturation: a crucial step in the replication of viral genomes. Romanowski V. Current issues in molecular virology (27-56). Croatie : InTech. (Article publié).

Articles de conférence

• *Boudreault S, Lemay G, Bisaillon M. (2020). Oncolytic reovirus’ μ2 protein governs modulation of cellular alternative splicing during infection and interacts with splicing factors and spliceosomal proteins. Riboclub Annual Meeting 2020 - RNA Biology and Technology – The Current Pandemic and Beyond. (Article publié).
• *Boudreault S, Lemay G, Bisaillon M. (2020). Reovirus modulates host cell alternative splicing landscape during infection through the μ2 protein. Riboclub 20th anniversary and Canada Gairdner International Symposium. (Article publié).
• C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2019). RiboClub 20th Anniversary and Canada Gairdner International Symposium. (Article accepté).
• C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2019). Changes in host cell gene expression levels and alternative splicing during Flavivirus infections. 69th Annual Conference of the Canadian Society of Microbiologists. (Article accepté).
• C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2019). Comparaison des changements d’expression des gènes et d’épissage alternatif de la cellule hôte lors d’une infection avec différents Flavivirus. 48e Journée scientifique de la FMSS. (Article publié).
• Claudio Jeldres, Sabrina Bouchard, Martin Bisaillon. (2018). Dissecting the expression landscape of genitourinary cancers. American Society of Clinical Society (ASCO) Annual Meeting. (Article publié).
• C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2018). Modulations of the host cell transcriptome upon infection with Kunjin, Zika and Yellow Fever viruses. 31st Annual Canadian Student Health Research Forum. (Article publié).
• Claudio Jeldres, Sabrina Bouchard, Martin Bisaillon. (2018). Transcriptome-wide analysis of alternative splicing events in bladder cancer: Novel biomarkers discovery for early diagnosis. American Society of Clinical Society (ASCO) Annual Meeting. (Article publié).
• C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2017). Flaviviruses modulate gene expression and alternative splicing in infected cells. 18th RiboClub Annual Meeting. (Article publié).
• C. Brand, K. Votaw, M. McCullagh, B. Geiss, M. Bisaillon. (2016). Characterization of the interaction between the NS3 and NS5 proteins within the West Nile virus replication complex. 19th Annual Chemistry and Biochemistry Graduate Research Conference. (Article publié).
• Boudreault S, Thibault P, Durand M, Lapointe E, Lemay G, Bisaillon M. (2016). Reovirus Infection Alters Host Cell Alternative Splicing Landscape. 6th European Congress of Virology (ECV). (Article publié).
• C. Brand, K. Votaw, M. McCullagh, B. Geiss, M. Bisaillon. (2016). Study of the West Nile virus RNA replication complex. 17th RiboClub Annual Meeting. (Article publié).
• Boudreault S, Thibault P, Durand M, Lapointe E, Garant J-M, Perreault J-P, Scott M, Lemay G, Bisaillon M. (2015). Alternative Splicing Modifications Triggered by Reovirus Infection. Chemistry and Biochemistry Graduate Research Conference (CBGRC). (Article publié).
• Boudreault S, Côté S, Lavoie D, Durand M, Lapointe E, Thibault P, Sandekian V, Bisaillon M, Lemay G. (2015). Combination of classical genetics, reverse genetics and transcriptomics to study reovirus'interferon sensitivity and host-cell response. Cytokine 2015 - Symphonies in Health and Disease - Third annual Meeting of the International cytokine and Interferon Society (ICIS). (Article publié).
• Rouleau S, Bisaillon M, Perreault JP. (2014). Sequence Specific Modulation of G-Quadruplex Folding. 19th Annual Meeting of the RNA Society. (Article publié).
• Jodoin R, Beaudoin JD, Perreault JP, Bisaillon M. (2013). A predictive value optimizing the evaluation of biological RNA G-quadruplexes formation. 18th Annual Meeting of the RNA Society. (Article publié).
• Picard-Jean F, Bouchard S, Larivée G, Bisaillon M. (2012). HCV replicon inhibition by the human Lactoferrin is mediated by NS3 ATPase/Helicase inhibition. 19th International Symposium on Hepatitis C Virus and Related Viruses. (Article publié).
• Picard-Jean F, Bouchard S, Larivée G, Bisaillon M. (2011). Lactoferrin inhibits the HCV NS3 ATPase/Helicase protein which impairs HCV replicon replication. 18th International Symposium on Hepatitis C Virus and Related Viruses. (Article publié).
• Picard-Jean F, Shuto S, Bisaillon, M. (2011). mRNA Capping is Inhibited by the Immunosuppressive Agent Mizoribine Monophosphate. RNA Meeting. (Article publié).
• Picard-Jean F, Shuto S, Bisaillon M. (2010). Can mizoribine monophosphate also be an RNA capping inhibitor ?. Gordon research conferences. (Article publié).
• Soulière MF, Perreault JP, Bisaillon M. (2010). Cap-recognition Mode of the viral D10 Decapping Enzyme. EMBL Conference: The Complex life of mRNA: from synthesis to decay. EMBL Conference. (Article publié).
• Issur M, Despins S, Bougie I, Bisaillon M. (2010). Nucleotide analogs and molecular modeling studies reveal key interactions involved in substrate recognition by the yeast RNA triphosphatase. 24th Annual Symposium of the Protein Society. (Article publié).
• Reymond C, Bisaillon M, Perreault JP. (2009). Decipher the folding pathway of a catalytic RNA. RNA Society 14th annual meeting. (Article publié).
• Picard-Jean F, Bisaillon M. (2009). Pleiotropic activity of ribavirin on HVC: Ribavirin-triphosphatae can support the NS3-mediated dsRNA unwinding activity. 16th International Symposium on Hepatitis C virus and related viruses. (Article publié).
• Dubé A, Baumstark T, Bisaillon M, Perreault JP. (2009). Structural differences between the two RNA strands of peach latent mosaic viroid. American Society for Virology 28th annual meeting. (Article publié).
• Soulière M, Perreault JP, Bisaillon M. (2008). Characterization of the vaccinia virus D10 decapping enzyme. RNA 2008. (Article publié).

Autres contributions

Activités de collaboration internationale

• Collaborator. États-Unis.

Présentations

• *Boudreault S, Lemay G, Bisaillon M. (2019). Oncolytic reovirus modulates host cell alternative splicing landscape during infection through the μ2 protein. The American Society for Virology's 38th Annual meeting. États-Unis
• C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2018). Kunjin, Zika and Yellow Fever viruses differentially alter gene expression and alternative splicing in U87 glioblastoma cells. 37th American Society for Virology Annual Meeting. College Park, MD, États-Unis
• *C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2018). Modulations du transcriptome de la cellule hôte suite à l’infection avec le virus Zika. 86e Congrès de l’Acfas. Chicoutimi, Qc, Canada
• *Boudreault S, Lemay G, Bisaillon M. (2018). Reovirus Infection Alters Host Cell Alternative Splicing Landscape. The American Society for Virology's 37th Annual meeting. États-Unis
• C. Brand, K. Votaw, M. McCullagh, B. Geiss, M. Bisaillon. (2017). Caractérisation de l’interaction entre les protéines NS3 et NS5 dans le complexe de réplication du virus du Nil occidental. 85e Congrès de l’Acfas. Montréal, Qc, Canada
• Sabrina Bouchard, Dominique Dorion, Jean-Pierre-Perreault, Martin Bisaillon. (2017). Focusing on cancer hallmarks: head and neck cancer biomarkers discovery. Journée Phare 2017: Congrès Québécois en sciences de la santé. Bromont, Qc, Canada
• C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2017). Les Flavivirus modulent l’expression des gènes et l’épissage alternatif de leurs cellules hôtes. 9e Journée Phare. Bromont, Qc, Canada
• *C. Brand, K. Bullard, B. Geiss, M. Bisaillon. (2017). Étude des changements d’expression des gènes et d’épissage alternatif suite à l’infection avec différents Flavivirus. 10e Congrès Armand Frappier. Orford, Qc, Canada
• *C. Brand, K. Votaw, M. McCullagh, B. Geiss, M. Bisaillon. (2016). L’interaction entre les protéines NS3 et NS5 du virus du Nil occidental - une nouvelle cible pour le développement de composés antiviraux?. 8e Journée Phare. Bromont, Qc, Canada
• *Simon Boudreault et Martin Bisaillon. (2016). Modulation de l’épissage alternatif de la cellule-hôte lors d’une infection virale. Journée Simon-Pierre Noël 2016 du département de biochimie de l'Université de Montréal. Canada
• (2012). La synthèse de la structure coiffe des ARNm représente une cible potentielle pour le développement d’inhibiteurs novateurs. Guest speaker / Seminar series / Dépt. de microbiology et immunologie / Université de Montréal. Montréal, Canada
• (2011). RNA Cap Recognition by the Vaccinia Virus D10 Decapping Enzyme. American Society for Microbiology Conference on Viral Genome Replication. Banff, Canada
• (2010). Développement d'inhibiteurs contre la synthèse de la structure coiffe des ARNm. Guest speaker / Seminar series / Dépt. de biochimie / Université de Montréal. Montreal, Canada
• Moheshwarnath Issur. (2009). Identification of the flaviviral RNA guanylyltransferase involved in the synthesis of the viral RNA cap structure. American Society for Virology 28th annual meeting. Vancouver, Canada
• Marie Soulière. (2009). Kinetic and mechanistic characterization of viral capping and decapping enzymes. Guest speaker. Innsbruck, Autriche
• (2009). Nucleotide analogs and molecular modeling studies to understand enzymes involved in RNA cap synthesis. Guest speaker. Prince George, Canada
• (2009). Nucleotide analogs and molecular modeling studies to understand enzymes involved in RNA cap synthesis. Guest speaker. Fort Collins, États-Unis
• Marie Soulière. (2009). Two-metal ion mechanism for the vaccinia virus D10 decapping enzyme. American Society for Virology 28th annual meeting. Vancouver, Canada