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Taha Azad

Professeur, Faculté de médecine et des sciences de la santé
FMSS Dép. de microbiologie et infectiologie

Présentation

Sujet de recherche

Cancer du poumon, Cancer du sein, Chimiothérapie, Immunothérapie

Disciplines de recherche

Biologie moléculaire, Virologie

Mots-clés

Synthetic biology, Oncolytic virus, Biosensor development

Intérêts de recherche

Synthetic biology (SynBio) is a multidisciplinary area of research that seeks to create new biological parts, devices, and systems, or to redesign systems that are already found in nature. In our lab, we use synthetic biology to develop novel therapeutics for cancer research and treatment, as well as infectious disease research.

Recherche clinique

Langues parlées et écrites

Anglais, persan

Diplômes

(2019). (Doctorat, ). Queen's University at Kingston.

(2016). (Maîtrise avec mémoire, ). Queen's University at Kingston.

(2014). Tarbiat Modares University (Maîtrise avec mémoire, ).

(2011). (Baccalauréat, ). University of Tehran.

Expérience académique

Assistant Professor. (2023-). Université de Sherbrooke. Canada.

Postdoctoral Fellow. (2019-2023). Ottawa Hospital Research Institute. Canada.

Research Assistant. (2015-2019). Queen's University at Kingston. Canada.

Teacher assistant. (2018-2019). Queen's University at Kingston. Canada.

Research Assistant. (2013-2014).

Prix et distinctions

  • (2023) Worton Researcher in Training Award. Ottawa Hospital Research Institute. (Prix).
  • (2022) CIHR Fellowship. Instituts de recherche en santé du Canada. (Prix).
  • (2022) Mitacs Fellowship. Ottawa Hospital Research Institute. (Prix).
  • (2021) Banting Postdoctoral Fellowship. CIHR. (Prix).
  • (2021) Governor General's Gold Medal. Queens University. (Prix).
  • (2019) International Tuition Award-. Queen's University at Kingston. (Prix).
  • (2019) The Robert Kisilevsky Fund for Research Education. Queen's University at Kingston. (Prix).
  • (2019) One Gold and a Silver Medal for the best research in the CIHR National Student Research Competition. CIHR. (Prix).
  • (2019) Qualified in a global competition to participate in the 68th Lindau Nobel Laureate Meeting for young scientists. Lindau Nobel Laureate Meeting- http://www.cihr-irsc.gc.ca/e/50989.html. (Prix).
  • (2019) Vanier Canada Graduate Scholarships (My application was ranked 1st out of 190 applications considered by the CIHR Vanier CGS selection committee). CIHR. (Prix).
  • (2018) The Robert Kisilevsky Researech Award. Queen's University at Kingston. (Prix).
  • (2018) The Deans' Awards for Academic Achievement/Canadian Student Health Research Forum Awar. Queen's University at Kingston. (Prix).
  • (2018) Ontario Graduate Scholarship (the quota for Queen's University is only 6 students per year). Queen's University at Kingston. (Prix).
  • (2017) Queen’s Graduate Award, 2016-2017. Queen's University at Kingston. (Prix).
  • (2016) Queen’s Graduate Award, 2015-2016. Queen's University at Kingston. (Prix).
  • (2014) Ranked 1st student in M.Sc. Tarbiat Modares University. (Honneur).
  • (2014) Gold medal winner in the National Biology Olympiad. Ministry of Education. (Prix).
  • (2014) Member of the Iranian National Foundation of Elites. Presidency of Iran National Elites Foundation. (Prix).
  • (2007) Student Grant Award. National Congress on Medicinal Plants, Kish Island, Iran,. (Prix).
  • (2005) Ranked 2nd in the Nationwide University Entrance Exam among 18,612 participants in Iran. Ministry of Education. (Honneur).
  • (2005) Silver medal winner in the National Biology Olympiad. Ministry of Education. (Honneur).
  • Scholarships for the Next Generation of Scientists. Cancer Research Society. (Prix).
  • Terry Fox new investigator award. terry fox research institute. (Prix).

Financement

  • Subvention. (Obtenu). Chercheur principal. Bioengineering viruses to create safer and more effective oncolytic viruses. Instituts de Recherche en Santé du Canada (IRSC). 986 850 $. (2023-2028)
  • Subvention. (Obtenu). Candidat principal. Scholarships for the Next Generation of Scientists. Cancer Research Society. CRS NGS. 170 000 $. (2023-2026)
  • Subvention. (Obtenu). Candidat principal. Developing Novel Oncolytic Viruses as Therapeutic Tools for Pediatric Brain Tumors. Fondation Terry Fox (La). New investigator. 442 000 $. (2023-2026)
  • Subvention. (Obtenu). Candidat principal. Startup Fund. Université de Sherbrooke. Startup package. 170 000 $. (2023-2025)
  • Subvention. (Obtenu). Cochercheur. Development of an oncolytic virus expressing NLRC5-super activator (NLRC5-SA) for cancer. Cancer Research Institute (IRCUS). 25 000 $. (2023-2024)
  • Bourse de recherche. (Obtenu). Cochercheur. Shaping the immunogenicity and efficient range of oncolytic vaccinia virus by the programmed release of therapeutically active, self-amplifying RNA containing virus-like-particles. Mitacs. Mitacs Elevate. 130 000 $. (2022-2024)
  • Bourse de recherche. (Terminé). Candidat principal. CIHR post-doctoral Fellowship. Instituts de Recherche en Santé du Canada (IRSC). CIHR PDF. 45 000 $. (2022-2023)
  • Subvention. (Terminé). Cochercheur. Development of Vaccines to Prevent SARS-CoV-2 Infection in High Risk Individuals. Instituts de Recherche en Santé du Canada (IRSC). Fast response. 1 936 150 $. (2020-2023)
  • Subvention. (Terminé). Collaborateur. Establishment of NanoLuc complementation reporter-based biosensor for measuring ACE2 and SARS-CoV-2 spike protein receptor-binding domain (RBD) interaction (Nominated PI Dr. Diallo). Instituts de Recherche en Santé du Canada (IRSC). Fast response. 440 000 $. (2020-2022)
  • Bourse de recherche. (Terminé). Candidat principal. Combined oncolytic virotherapy and RTKs signaling targeting for cancer treatment- Banting Postdoctoral Fellowship. Instituts de Recherche en Santé du Canada (IRSC). Banting PDF. 140 000 $. (2020-2021)
  • Subvention. (Terminé). Cocandidat. Development of a biosensor for high throughput screening of novel compounds targeting ezrin for breast cancer therapy. (Nominated PI Dr. Greer). Institut de recherche de la Société canadienne du cancer (IRSCC). CCSRI innovation grant. 200 000 $. (2018-2020)
  • Bourse de recherche. (Terminé). Cocandidat. Mitacs Accelerate Fellowship. Mitacs. Mitacs accelerate. 45 000 $. (2019-2020)
  • Bourse d’études. (Terminé). Candidat principal. Vanier Canada Graduate Scholarships. Instituts de Recherche en Santé du Canada (IRSC). Vanier-Banting program. 150 000 $. (2017-2019)
  • Bourse d’études. (Terminé). Candidat principal. Ontario Graduate Scholarship. Ministry of Colleges and Universities. Ontario Graduate Scholarship (OGS) Program. 15 000 $. (2017-2018)
  • Bourse d’études. (Terminé). Candidat principal. Ontario Graduate Scholarship. Ministry of Colleges and Universities. Ontario Graduate Scholarship (OGS) Program. 15 000 $. (2015-2016)

Publications

Articles de revue

  • J. T Whelan, R. Singaravelu, F. Wang, Adrian Pelin, L. A Tamming, G. Pugliese, N. T Martin, M. Crupi, Julia Petryk, B. Austin, X. He, R. Marius, C. Jones, E. F. Brown, N. Alluqmani, A. Chen, S. Boulton, M. Huh, M. Y Tang, E. Scut, J. Diallo, T. Azad, B. D Lichty, C S Ilkow and J Bell. (2023). CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX. Frontiers in immunology 287 567-599. (Article publié).
  • S. Boulton, M. JF Crupi, S. Singh, M. E Carter-Timofte, T. Azad, B. C Organ, X. He, R. Gill, S. Neault, T. Jamieson, J. Dave, N. Kurmasheva, B. Austin, J. Petryk, R. Singaravelu, B. Zhen Huang, N. Franco, K. Babu, R. J Parks, C. S Ilkow, D. Olagnier, J. C Bell. (2023). EPAC Antagonism Induces Broad-Spectrum Inhibition of Virus Infectivity via Remodeling of Actin Complexes. Journal of Biological Chemistry 299 (6), 22. (Article publié).
  • N. T. Martin, M. J. F. Crupi, Z. Taha, J. Poutou, J. Whelan, S. Vallati, J. Petryk, R. Marius, B. Austin, T. Azad, M. Boulanger, T. Burgess, I. Sanders, C. Victoor, B. C. Dickinson, J-S Diallo, C. S. Ilkow and J. C. Bell. (2023). Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy. Pharmaceuticals 16 (5), 709-732. (Article publié).
  • A. Surendran, M. Jamalkhah, J. Poutou, R. Birtch,C. Lawson, J. Dave, M. Crupi, V. Taylor, J. Petryk, C. Souza, N. Moodie, J. Billingsley, B. Austin, N. Cormack, N. Blamey, R. Rezae, C. Mccloskey, E. Fekete, H. Birdi, S. Neault, T. Jamieson, S. Tucker, T. Azad, B. Vanderhyden, L. Tai, J. Bell, C. Ilkow. (2023). Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment. Frontiers in Immunology 255 151-191. (Article publié).
  • T. Kazmirchuk, C. Jost, T. Withey, T. Gessese, T. Azad, B. Samanfar, F. Dehne and A. Golshani. (2023). Peptides of a Feather: How Computation Is Taking Peptide Therapeutics under Its Wing. Genes 14 11-94.
  • T. Azad, R. Rezaei, R. Singaravelu, A. Pelin, S. Boulton, J. Petryk, K. Onsu, N. T. Martin, V. Hoskin, M. Ghahremani, M. Marotel, R. Marius, X. He, M. J. F. Crupi, H. Hoang, A. Nik-Akhtar, M. Ahmadi, N. Zamani, A. Golshani, T. Alain, P. Greer, M. Ardolino, B. C. Dickinson, L-H. Tai, C. S. Ilkow & J. C. Bell. (2023). Synthetic biology approaches to improve the safety and efficacy of oncolytic virus therapies. Nature Communications 14 30-88. (Article publié).
  • Hajikarimlou M, Hooshyar M, Moutaoufik MT, Aly KA, Azad T, Takallou S, Jagadeesan S, Phanse S, Said KB, Samanfar B, Bell JC. (2022). A computational approach to rapidly design peptides that detect SARS-CoV-2 surface protein S. NAR genomics and bioinformatics 44 11-56. (Article publié).
  • S. Ghavami, P. Abrishami, S. Afifi, A. Sereshki, M. Akbari, A. Akbariansaravi, E. Alarcon, A. Alavi, P. Alipour, T. Azad, Z. Azizi, Majid Bahrami, M. Balibegloo, A. Baniasadi, et al. (2022). Diversity, equity and inclusion in autophagy research. Autophagy 59 1232-1249. DOI. (Article publié).
  • Z. Taha, R. Arulanandam, G. Maznyi, E. Godbout, M. E. Carter-Timofte, N. Kurmasheva, L. S. Reinert, A. Chen, M. J.F. Crupi, S. Boulton, G. Laroche, A. Phan, N. Alluqmani, A. Jirovec, A. Acal, E.F. Brown, R. Singaravelu, J. Petryk, M. Idorn, K. G. Potts, H. Todesco, D. J. Mahoney, C. S. Ilkow, P. Giguère, T. Alain, M. Côté, S. R. Paludan, D. Olagnier, J. C. Bell, T. Azad (senior author) and J-S Diallo. (2022). Identification of FDA-approved Bifonazole as SARS-CoV-2 blocking agent following a bioreporter drug screen. Molecular Therapy-Cell 675 32. (Article publié).
  • M. Crupi, Z. Taha, T. Janssen, J. Petryk, S. Boulton, N. Alluqmani, A. Jirovec, O. Kassas, S. Khan, S. Vallati, E. Lee, B. Zhen Huang, M. Huh, L. Pikor, X. He, R. Marius, B. Austin, J. Duong, A. Pelin, S. Neault, T. Azad, C. J. Breitbach, D. F. Stojdl, M. F. Burgess, S. McComb, R. Auer, J. Diallo, C. S. Ilkow and J. Bell. (2022). Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer. Frontiers in immunology 123 456-491. (Article publié).
  • T. Azad, R. Rezaei,..., J. Cowan, D. Cameron, C. S. Ilkow,. (2021). A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion. Nanomaterials 11 807-821. (Article publié).
  • Carter-Timofte, M.; Arulanandam, R.; Kurmasheva , N.; Taha, Z.; Cassin, L.; Jacobs, D.; Maznyi, G.; Azad, T., Manja; P., Soren; Bell, J.; Seguin, J.; Sabourin, L.; Cote, M.; Diallo, JS; Alain, T.; Olagnier, D. (2021). Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern. ACS Infectious Diseases 7 23-45. (Article publié).
  • E. Brown, R. Rezaei, T. Jamieson, J. Dave, N. Martin, R. Singaravelu,..., J. Diallo, J. Bell, C. S. Ilkow, T. Azad. (2021). Characterization of Critical Determinants of ACE2–SARS CoV-2 RBD Interaction. International Journal of Molecular Sciences 7 1-25. (Article publié).
  • T. Jamieson, J. Poutou, R. Marius, X. He, R. Rezaei, T. Azad, CS. Ilkow. (2021). Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection. Journal of Visualized Experiments 43 56-98. (Article publié).
  • R. Rezaei, A. Surendran, R. Singaravelu, T. Jamieson, P. Taklifi, J. Poutou, T. Azad, Carolina S. Ilkow,. (2021). Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter. Journal of Visualized Experiments 76 54-59. (Article publié).
  • M. Razzaghi, A. Homaei, F. Vianello, T. Azad, T. Sharma, Ashok K. Nadda, R. Stevanato, M. Bilal, and H. Iqbal. (2021). Industrial applications of immobilized nano-biocatalysts. Bioprocess and Biosystems Engineering 138 1-15. (Article publié).
  • T. Azad, H. Rensburg, J. Morgan, R. Rezaei, M. Crupi, R Chen, M. Ghahremani, M. Jamalkhah, N. Forbes, C. Ilkow, J. Bell. (2021). Luciferase-based biosensors in the era of the COVID-19 pandemic. ACS Nano / Nano au 1 1-29. (Article publié).
  • T. Azad, R. Singaravelu, Z. Taha, T. Jamieson, S. Boulton, M.Crupi, N. Martin, E. Brown, J. Poutou, M. Ghahremani, A. Pelin, K. Nouri, R. Rezaei, A. Gingras, D. Cameron, P. Greer, C. S. Ilkowa, J. Dialloa, J. C. Bell. (2021). Nanoluciferase complementation-based biosensor reveals the importance of N- linked glycosylation of SARS-CoV-2 Spike for viral entry. Molecular Therapy-Cell Press 29 1984-2000. (Article publié).
  • M. Power, T. Azad, J. Bell, A. MacLean. (2021). Plant-based expression of SARS-CoV-2 antigens for use in an oral vaccine. Journal of Food Science and Nutrition 65 33-38. (Article accepté).
  • T. Azad, R. Singaravelu, E. Brown, Z. Taha, R. Rezaei, R. Arulanandam, S. Boulton, J-S Diallo, C. S.Ilkowab, J.Bell. (2021). SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition. Biosensors and Bioelectronics 180 113122-113139. (Article publié).
  • S. Boulton, Y. Poutou Paumier, N. Martin, T. Azad (first equal contribution), R. Singaravelu, M. Crupi, T. Jamieson, X. He, R. Marius, J. Petryk, C. Souza, B. Austin, S. Khan, A. Pelin, R. Rezaei, A Surendran, J. Diallo, R. Auer, J. Angel, D. Cameron, R. Lapointe, K. Potts, D. Mahoney, J. Bell, C. Ilkow. (2021). Single dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection. Molecular Therapy - Cell 787 7876-7898. (Article publié).
  • A. Sadremomtaz, M. Al-Dahmani, A. Ruiz-Moreno, A. Monti, C. Wang,T. Azad, J. Bell, N. Doti, M. Velasco,J. de Jong, S. Alexander, H. Goor, Harry, M. Groves, Matthew. (2021). Synthetic Peptides that antagonise the Angiotensin-Converting Enzyme-2 (ACE-2) interaction with SARS-CoV-2 receptor binding spike protein. Journal of Medicinal Chemistry 87 878-898. (Article publié).
  • M Wedge, V. Jennings, M Crupi, J Poutou, T. Jamieson, G. Pugliese, C. Souza, J. Petryk, B. Laight, M. Boileau, N. Alluqmani, H. E. McKay, L. Pikor, S. Tahsin Khan, T. Azad, R. Rezaei, B. Austin, X. He, D. Mansfield, A. Pelin, E Rose, E. Brown, N. Crawford, A. Alkayyal, A. Surendran, R. Singaravelu, D. G. Roy, B. McSweeney, M. Cottee, E. J. Jacobus, B. Geoffrion, K. J. Rayner, A. Chatterjee, Rebecca G. Migneco, M. C. Auer, Jean-Simon Diallo, D. Gibbings, B. Oever, A. Melcher, J C. Bell, and C. S. Ilkow. (2021). Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy. Nature Communications 78 1-32. (Article publié).
  • T. Azad, R. Rezaei, A. Surendran, R. Singaravelu, S. Boulton, J. Dave, J. Bell and C. S. Ilkow . (2020). Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis. Cancers 13 10. (Article publié).
  • T. Azad, R. Singaravelu, M.F. Crupi, T. Jamieson, J. Dave, E.F. Brown, R. Rezaei, Z. Taha, S. Boulton, N. Martin, A. Surendran, J. Poutou, M. Ghahremani, K. Nouri, J. Whelan, J. Duong, S. Tucker, J. Diallo, J. C. Bell and C. S. Ilkow. (2020). Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization. Membranes - -. (Article publié).
  • X. Guo , Y. Sun , T. Azad , H. Rensburg , J. , S. , P. Liu , Z. Lv , M. Zhan , L. Lu , Y. Zhou , X. Ma , X. Zhang , X. Yang , L. Xue. (2020). Rox8 promotes miRNA-dependent yki mRNA decay. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 10 25. (Article publié).
  • T. Azad, K. Nouri, H. J Janse van Rensburg, S. M. Maritan, T. Montminy, Y. Hao, J. Yu, P. Khanal, L. M. Mulligan, X. Yang. (2019). A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis. Oncogene-Nature Series 15 18. (Article publié).
  • K. Nouri, T. Azad (equal contribution first author), E. Lightbody, P. Khanal, C. Nicol, X. Yang. (2019). A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion. FASEB Journal - 46. (Article publié).
  • K. Nouri; T. Azad; M. Ling; Janse H van Rensburg; H. Shen; J. Zhang, X. Yang. (2019). Identification of Celastrol as a novel YAP-TEAD inhibitor for cancer therapy by high throughput screening with ultrasensitive YAP/TAZ-TEAD biosensors. Cancers 13 25. (Article publié).
  • T. Azad, M. Ghahremani, X. Yang. (2019). The Role of YAP and TAZ in Angiogenesis and Vascular Mimicry. Cells 87 407-429. (Article publié).
  • T. Azad , H. J Rensburg , E. Lightbody, B. Naveu , A. Champagne , A. Ghaffari , V. Kay , Y. Hao , H. Shen , B. Yeung , A. Croy , K. Guan , F. Pouliot , J. Zhang , C. Nicol, X. Yang. (2018). A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nature Communications 24 1061-1070. (Article publié).
  • T. Azad, K. Nouri (equal contribution), H. J. Rensburg, Y. Hao, X. Yang. (2018). Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor. JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols 18 1-6. (Article publié).
  • Y. Zhao , T. Montminy , T. Azad (equal contribution),E. Lightbody , Y. Hao , S. SenGupta , E. Asselin , C. J. Nicol. (2018). PI3K Regulates YAP/TAZ in Mammary Tumorigenesis through Multiple Signaling Pathways. Molecular Cancer Research 26 1046-1058. (Article publié).
  • H. Rensburg, D. Lai, T. Azad (equal contribution), Y. Hao, Xi. Yang. (2018). TAZ enhances mammary cell proliferation in 3D culture through transcriptional regulation of IRS1. Cellular Signalling 14 12-22. (Article publié).
  • H. J Rensburg, T. Azad, M. Ling, Y. Hao, B. Snetsinger, P. Khanal, L. M Minassian, C. H. Graham, M. J Rauh and X. Yang. (2018). The Hippo pathway component TAZ promotes immune evasion in human cancer through PD-L1. Cancer Research-AACR Publications 13 31-39. (Article publié).
  • T. Bahmani ; S. Gholami; A. Mostafaie; E. Karimi; Z. Hoseinkhani; T. Azad; H. Mahdizadeh & K. Mansouri. (2017). Olfactory Epithelium as an Infinitive Source of Neural Stem Cells for Derivation of Inner Ear Hair Cells. International Journal of Morphology 11 413-419. (Article publié).
  • S.Rouholamini, N.Motamed, E.Birjandian, T.Azad, K.Omidfar. (2015). Inhibition of mir-15a Gene Expression by Silibinin in MCF-7 Breast Cancer Cell Line. International Journal of Current Research and Academic Review 12 288-296. (Article publié).
  • R.Hemmati, S.Hosseinkhani, R.Sajedi, T.Azad, A.Tashakor, N.Bakhtiari, F.Ataei. (2015). Luciferin Regenerating Enzyme mediatesfirefly luciferase activation through direct effects of D-cysteine onluciferase structure and activity. Photochemistry and Photobiology 13 828–836. (Article publié).
  • T.Azad, A.Tashakor, F.Rahmati, R.Hemmati, S.Hosseinkhani. (2015). Oscillation of apoptosome formation through assembly of truncated Apaf-1. European Journal of Pharmacology 21 64-71. (Article publié).
  • T. Azad, A.Tashakor, M.Ghahremani, R.Hemmati, F.Ataei, S. Hosseinkhani. (2014). Apoptotic protease-activating factor 1 as a liable gene for spontaneous mutations in vitro. Progress in Biological Science 5 261-273. (Article publié).
  • T.Azad, A.Tashakor, R.Hemmati, S.Hosseinkhni. (2014). Investigation the effect of an Apaf-1 derivative on caspasein HEK293T cells. Teb journal 3 57-65. (Article publié).
  • M. Ghahremani, F. Ghanati, F. Bernard, T. Azad, M. Gholami, M. Safari. (2014). Ornithine-induced increase of proline and polyamines contents in tobacco cells under salinity conditions. Australian Journal of Crop Science 6 91-96. (Article publié).
  • T.Azad, A.Tashakor, S.Hosseinkhani. (2014). Split-luciferase complementary assay: Applications, recent developmentsand future perspectives. Analytical and Bioanalytical Chemistry 16 5541-5560. (Article publié).
  • M.Ghahremani, F.Ghanati, F.Bernard, M.Gholami, T.Azad. (2013). Effects of exogenous ornithine enantiomerson tobacco cells under salinity conditions. Progress in biological Science 87 100-107. (Article publié).

Livres

  • E. khosravi,T. Azad,. (2019). Comparative animal biology for High school students- Tehran, Iran, ISBN 978-964-355-713-3. Iran : Razamandegan publications. (Article publié).
  • T. Azad, R. Khanjari. (2018). Basic Biology for High School Students,Tehran, Iran, 2014, ISBN 978-600-5008-79-1. Iran : Kelke Moalem. (Article publié).
  • A. Nasri, K. Nasri. (2018). General Biology for High School Students, Tehran, Iran, ISBN:9786005506716. Iran : Kheili Sabz. (Article publié).
  • A. Tashakor, R. Hemmati, T. Azad. (2017). Biochemistry-Biophysics and Genetic Engineering, ISBN:9786006531670. Iran : Sobhan. (Article publié).
  • T. Azad, M. Tokazebani, M. Khakie, M. Manteghi. (2017). Genetics for High School Students, Tehran, Iran, 2014, ISBN 978-600-5008-66-1. Iran : Kelk publications. (Article publié).
  • T. Azad, M. Hosseinpour, M. Sharifian. (2010). General biology for college students (Volume1), Tehran, Iran, 2014, ISBN 978-600-5703-12-2. Taimaz. (Article publié).
  • T. Azad, S. Abarghoe, A. Taghi, P. Abolahi. (2010). General biology for college students (Volume 2), Tehran, Iran, 2014, ISBN 978-600-5703-13-9. Taimaz. (Article publié).
  • A. Shaghaiegh, M. Hadadi, H. Rahvareh, A. Keramat, H. Komshi,. (2010). The Biology Coloring Book- Tehran, Iran, ISBN 978-600-126-332-3. Ghalamchi. (Article publié).
  • Sh. Shahdin, T. Azad, and others. (2009). How to Prepare for Iranian University Entrance Exam (Volume 1)-Tehran, Iran, 2014, ISBN 9786001263712. Ghalamchi. (Article publié).
  • Sh. Shahdin, T. Azad, and others. (2009). How to Prepare for Iranian University Entrance Exam (Volume 2)-Tehran, Iran, 2014, ISBN 97869645097842. Ghalamchi. (Article publié).

Articles de magazine

  • T.Azad. (2010). How to succeed in the Iranian National Biology exam. Azmon.
  • T.Azad. (2009). How DNA Structure was discovered?. Dena (monthly biology magazine at University of Tehran (Iran).

Propriétés intellectuelles

Brevets

  • Xiaolong Yang Taha Azad Kazem Nouri. (2023). HIPPO PATHWAY BIOLUMINESCENT BIOSENSOR- YANG, Xiaolong; AZAD Taha; NOURI Kazem. 16177691. Canada. (Délivré).
  • ILKOW, Carolina, Solange; BELL, John, Cameron; WHELAN, Jack, Timothy; CRUPI, Mathieu, François, Joseph; DUONG, Jessie, Nhan; LICHTY, Brian, Dennis; ATHERTON, Matthew, John; WANG, Fuan; PAUMIER, Yoana, Poutou; BOULTON, Stephen, Donald; AZAD, Taha; SINGARAVELU, Ragunath. RECOMBINANT POLYPEPTIDES FOR PROGRAMMING EXTRACELLULAR VESICLES. CA2020/051630. États-Unis d'Amérique. (Délivré).

Autres contributions

Présentations

  • (2022). Conditionally replicating vaccinia virus platforms As alternatives to Modified Vaccinia Ankara for cancer immunotherapy. International oncolytic virus conference. Japon
  • (2022). Synthetic Biology: novel strategies for discovering new cancer therapeutics. Terry Fox Research Institute and Princess Margaret Cancer Centre Symposium. Toronto, Canada
  • (2021). Viral genome editing reveals non-essential genes in the development of a safe and efficient oncolytic platform. XXIII International Poxvirus, Asfarvirus, and Iridovirus Conference. Pennsylvania, États-Unis d'Amérique
  • (2020). Nanoluciferase complementation-based biosensor reveals the importance of N- linked glycosylation of SARS-CoV-2 Spike for viral entry. The Ottawa Hospital Research Institute Research Day. Ottawa, Canada
  • (2017). How Fireflies could be the key to fighting cancer?. Banting-Vanier Lecture Series https://www.queensu.ca/sgs/banting-vanier-lecture-series. Kingston, Canada
  • (2017). Identification of Novel Receptor Tyrosine Kinases (RTKs) Regulating the Hippo Signaling Pathway in Tumorigenesis (CIHR Gold Award Winner), Taha Azad, Helena Janse van Rensburg, Yawei Hao, Yang X. CIHR National Student Research Poster Competition. Winnipeg, Canada
  • (2016). "Identification of FGFR1 as a novel kinase regulating YAP oncoprotein", (CIHR Gold Award Winner), H. Janse van Rensburg, T.Azad (equal contribution) , J. Yu , Y. Hao, Kl. Guan, X. Yang. CIHR National Student Research Poster Competition. Winnipeg, Canada
  • (2016). “Detection of protein-protein interaction and intramoleculat conformational changes in Apaf-1 using split luciferase complementation assay”, A. Tashakor, M. Hosseinzadehkordi, T. Azad,. Protein Interaction in Biology, National University of Ireland. Galway, Irlande
  • (2014). "Split Luciferase Complementation Assay",Best English presentation award. 10th annual Meeting of the Biological Society. Tehran, Iran
  • (2013). "Design and characterization of a new firefly luciferase mutant by site-directed mutagenesis", A. Tashakor, T. Azad, S. Hosseinkhani, F. Jazayeri, M.A. Nasab. National Congress of Biological Sciences. Isfahan, Iran
  • (2013). "Detection Protein Protien Interaction, Using Firefly Luciferase", Best Poster Award,. 1st International Life Science Conference & 12th Iran Biophysical Chemistry Conference. Tabriz, Iran
  • (2013). "Investigation on the function of WD-40 domain in Apaf -1(apoptosis factor) by split luciferase complementation assay", T. Azad, A. Tashakor, S. Hosseinkhani, F. Ataei, M.T. Mahani. National Congress of Biological Sciences. Isfahan, Iran
  • (2013). "Role of electrostatic interactions in switching autoinhibited Apaf-1 molecule into active state", A. Tashakor, T. Azad, S. Hosseinkhani, F. Ataei, M.T. Mahani. National Congress of Biological Sciences. Isfahan, Iran
  • (2013). "Site-directed mutagenesis of firefly luciferase: Effect of Charge Distribution on active site",T. Azad, A. Tashakor, S. Hosseinkhani, F. Jazaieri, M.A. nasab. National Congress of Biological Sciences. Isfahan, Iran
  • (2013). “Effect of exogenous D-ornithine on antioxidant enzymes, viability, and growth of tobacco cells under salinity stress”, M. Ghahremani, F. Ghanati, T. Azad. 1st International Life Science Conference & 12th Iran Biophysical Chemistry Conference,. Tabriz, Iran
  • (2013). “Effect of exogenous D/L-ornithine on growth and putrescine and spermidine contents of tobacco cells (Nicotiana tabacum L. CV. Burley 21) under salinity stress”, M. Ghahremani, F. Ghanati, T. Azad. National Congress of Biological Science. Isfahan, Iran
  • (2012). “A plausible relationship between D-ornithine and resistance to salt stress in tobacco (Nicotiana tabacum L.) cells”, M. Ghahremani, F. Ghanati, T. Azad. National Congress on Medicinal Plants,. Kish Island, Iran
  • (2012). “Changes in proline content and lipid peroxidation level by salinity stress and D-ornithine application in tobacco (Nicotiana tabacum L.)”M. Ghahremani, F. Ghanati, T. Azad. 3rd Iranian Agricultural Biotecnology Conference. Mashhad, Iran